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2-Iminobenzimidazoline

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Identification
Molecular formula
C7H8N2O
CAS number
540-84-1
IUPAC name
1,3-dihydrobenzimidazol-2-one
State
State

At room temperature, 1,3-dihydrobenzimidazol-2-one is found in a solid state. It is commonly found in the form of crystalline powder, indicating its solid and stable nature under standard conditions.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
328.00
Boiling point (Kelvin)
601.15
General information
Molecular weight
134.16g/mol
Molar mass
134.1550g/mol
Density
1.3000g/cm3
Appearence

1,3-Dihydrobenzimidazol-2-one typically appears as a white to off-white crystalline powder. This compound is known to have a solid form at room temperature.

Comment on solubility

Solubility of 1,3-Dihydrobenzimidazol-2-one

1,3-Dihydrobenzimidazol-2-one exhibits interesting solubility characteristics that are important for its applications in various chemical processes. Here are some key points regarding its solubility:

  • Polar Solvents: This compound is generally more soluble in polar solvents such as water and dimethyl sulfoxide (DMSO) due to the presence of nitrogen atoms in its structure that can engage in hydrogen bonding.
  • Non-Polar Solvents: In contrast, its solubility in non-polar solvents like hexane or benzene is significantly lower, making it more hydrophilic in nature.
  • pH Sensitivity: The solubility may also vary with pH, as the presence of different ionization states can affect the compound’s ability to dissolve in aqueous environments.
  • Thermal Impact: Higher temperatures generally increase solubility in many substances, including 1,3-dihydrobenzimidazol-2-one, although specific data should be consulted for precise effects.

As a general observation, the solubility of 1,3-dihydrobenzimidazol-2-one can be summarized as:

  1. Better solubility in polar solvents.
  2. Limited solubility in non-polar solvents.
  3. Variable solubility based on pH levels.

Understanding the solubility profile of this compound is essential for researchers and practitioners to explore its full potential in medicinal chemistry and chemical manufacturing.

Interesting facts

Interesting Facts about 1,3-Dihydrobenzimidazol-2-one

1,3-Dihydrobenzimidazol-2-one is a fascinating compound with a variety of intriguing properties and applications. Below are some noteworthy aspects that highlight its significance in the field of chemistry:

  • Structure & Function: The structure of 1,3-dihydrobenzimidazol-2-one features a fused ring system that includes both a nitrogen and an aromatic benzene component. This unique configuration contributes to its chemical reactivity and potential utility in various synthetic pathways.
  • Biological Activity: This compound and its derivatives have been studied for their biological activities. They show promise as potential pharmacological agents, influencing pathways in areas such as antimicrobial and anticancer research.
  • Coordination Chemistry: 1,3-Dihydrobenzimidazol-2-one serves as an important ligand in coordination chemistry. It has the ability to form stable complexes with transition metals, making it valuable in catalysis and materials science.
  • Synthetic Versatility: The derivatives of this compound are versatile building blocks in organic synthesis. They can be modified through various chemical reactions, allowing chemists to design new compounds with tailored properties.
  • Research Applications: Current research includes exploring its use in organic light-emitting diodes (OLEDs), organic photovoltaics, and as a part of advanced materials, showcasing its multifaceted applications beyond traditional roles.

In summary, 1,3-dihydrobenzimidazol-2-one is more than just a chemical formula; it's a compound with diverse applications ranging from medicinal chemistry to materials science. As research continues to unveil its potential, the possibilities for this compound remain as dynamic as its structure.

Synonyms
2-Hydroxybenzimidazole
615-16-7
2-Benzimidazolol
o-Phenyleneurea
2H-Benzimidazol-2-one, 1,3-dihydro-
2-BENZIMIDAZOLINONE
2-Benzimidazolone
2(3H)-Benzimidazolone
1,3-Dihydro-2H-benzimidazol-2-one
2-Oxobenzimidazole
1H-Benzimidazol-2-ol
2H-Benzimidazol
Benzamidazole-2(3H)-one
2(3H)-Oxobenzimidazole
N,N'-(1,2-Phenyleneurea)
NSC 10383
NSC 178108
Urea, N,N'-(1,2-phenylene)-
1H-BENZO[D]IMIDAZOL-2-OL
EINECS 210-412-4
CV8118UZEW
AI3-60092
NSC-10383
2,3-Dihydro-2-oxo-1H-benzimidazole
NSC-178108
LANSOPRAZOLE IMPURITY D
EC 210-412-4
1H-BENZO(D)IMIDAZOL-2-OL
BENZIMIDAZOLOL [USP IMPURITY]
1,3-dihydro-2h-benzimidazole-2-one
LANSOPRAZOLE IMPURITY D [EP IMPURITY]
RABEPRAZOLE SODIUM IMPURITY K [EP IMPURITY]
BENZIMIDAZOLOL (USP IMPURITY)
LANSOPRAZOLE IMPURITY D (EP IMPURITY)
RABEPRAZOLE SODIUM IMPURITY K (EP IMPURITY)
210-412-4
1,3-dihydrobenzimidazol-2-one
102976-62-5
2(1H)-Benzimidazolone
MFCD00127894
2-Hydroxy-benzimidazol
benzimidazolinone
1H-Benzimidazol-2-ol(9CI)
benzimidazolin-2-one
2,3-dihydro-1H-1,3-benzodiazol-2-one
2-Hydroxy-1H-benzimidazole
CHEMBL2152713
1,3-dihydro-benzoimidazol-2-one
1H-benzo[d]imidazol-2(3H)-one
N,2-Phenyleneurea)
1,3-dihydro-2H-benzo[d]imidazol-2-one
WLN: T56 BNVNJ
2-.alpha.-Hydroxybenzimidazole
Urea,N'-(1,2-phenylene)-
SILNNFMWIMZVEQ-UHFFFAOYSA-
benzimidazol-2(3H)-one
Lansoprazole EP impurity D
UNII-CV8118UZEW
azaoxindole
1H-1,3-benzodiazol-2-ol
2,3-dihydrobenzimidazol-2-one
o-Phenylene urea
hydroxybenzimidazole
(3H)-benzimidazolone
2-hydroxybenzoimidazole
2-hydroxy benzimidazole
1H-benzimidazol-2-one
starbld0016990
benzimidazole, 2-hydroxy-
SCHEMBL37951
2-Hydroxybenzimidazole, 97%
1,3-dihydrobenzoimidazol-2-one
DTXSID0060642
HMS1783E17
BCP18291
NSC10383
BDBM50393071
NSC178108
STK056075
STL360330
2,3-dihydro-1H-benzimidazole-2-one
AKOS000269651
AKOS015920049
CS-W008003
GF-0113
HY-W008003
IH11727
PS-5766
DA-16144
PD065534
SY033248
DB-017416
H0739
NS00002447
EN300-17387
F12393
AF-834/25000580
AK-830/25033028
Q818479
Z56924489
F0728-0008
Lansoprazole impurity D;2,3-Dihydro-2-oxo-1H-benzimidazole;1,3-Dihydro-2H-benzimidazol-2-one