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Phthalidylphenylacetic acid

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Identification
Molecular formula
C15H9NO5
CAS number
82-03-5
IUPAC name
1,3-dioxo-2-phenyl-isoindoline-5-carboxylic acid
State
State

At room temperature, it is a solid.

Melting point (Celsius)
253.00
Melting point (Kelvin)
526.15
Boiling point (Celsius)
505.00
Boiling point (Kelvin)
778.15
General information
Molecular weight
267.24g/mol
Molar mass
267.2390g/mol
Density
1.5000g/cm3
Appearence

A crystalline solid with white to off-white appearance.

Comment on solubility

Solubility of 1,3-dioxo-2-phenyl-isoindoline-5-carboxylic acid

The solubility of 1,3-dioxo-2-phenyl-isoindoline-5-carboxylic acid can be quite intriguing, as it presents several notable characteristics:

  • Polarity: The presence of both carboxylic acid and carbonyl groups in the structure enhances its polarity, which plays a crucial role in its solubility.
  • Solvent Interaction: This compound is expected to be soluble in polar solvents such as water, due to the ability of the carboxylic group to form hydrogen bonds.
  • Weak Solubility in Organic Solvents: Conversely, solubility in non-polar solvents may be limited, as the hydrophilic nature of its functional groups contrasts sharply with the properties of non-polar substances.
  • pH Sensitivity: The solubility might also vary with pH; in basic conditions, the carboxylic group can deprotonate, potentially increasing its solubility in aqueous solutions.

In summary, while 1,3-dioxo-2-phenyl-isoindoline-5-carboxylic acid is likely to display favorable solubility in polar solvents, its solubility profile is strongly influenced by solvent type and pH conditions. Understanding these aspects is essential for applications and reactivity in chemical processes.

Interesting facts

Interesting Facts about 1,3-Dioxo-2-phenyl-isoindoline-5-carboxylic Acid

1,3-Dioxo-2-phenyl-isoindoline-5-carboxylic acid is a fascinating compound with a unique structure that belongs to the isoindoline family. Here are some engaging facts about this compound:

  • Diverse Applications: This compound is notable for its potential applications in pharmaceuticals, particularly in the development of antibiotics and anti-cancer agents.
  • Structural Features: The presence of a dioxo functional group contributes to the compound's reactivity and versatility in organic synthesis.
  • Role in Organic Chemistry: Isoindoline derivatives, including this compound, play a significant role in the study of heterocyclic chemistry and the design of new materials.
  • Potential Biological Activity: Research has suggested that derivatives of isoindoline compounds may exhibit a range of biological activities, making them targets for drug discovery efforts.
  • Sensitivity to Environmental Factors: The stability and reactivity of this compound can be influenced by factors such as pH and temperature, which are crucial considerations in experimental settings.

As one delves deeper into the chemistry of 1,3-dioxo-2-phenyl-isoindoline-5-carboxylic acid, the compound reveals itself as a promising candidate for future research, bridging the gap between organic synthesis and medicinal chemistry. The ongoing exploration in this area highlights the importance of such compounds in advancing our understanding of chemical interactions and potential therapeutic applications.

Synonyms
4649-27-8
1,3-DIOXO-2-PHENYLISOINDOLINE-5-CARBOXYLIC ACID
1,3-Dioxo-2-phenyl-2,3-dihydro-1H-isoindole-5-carboxylic acid
4-carboxy-N-phenylphthalimide
1,3-dioxo-2-phenylisoindole-5-carboxylic acid
1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1,3-dioxo-2-phenyl-
TF9AXG6CBX
MFCD00427538
N-Phenylphthalimide-4-carboxylic acid
CHEMBL3746724
NSC-180808
NSC180808
NSC 180808
UNII-TF9AXG6CBX
1,3-dioxo-2-phenyl-5-isoindolinecarboxylic acid
Oprea1_328667
Oprea1_553696
SCHEMBL1618163
DTXSID20196853
LJQKDUGNSCMZSJ-UHFFFAOYSA-N
ALBB-010579
BDBM50589131
AKOS000269563
AT29790
SB64176
LS-03589
EN300-235821
AB00074703-01
AG-690/33384048
F1018-1399