Skip to main content

Etoposide

ADVERTISEMENT
Identification
Molecular formula
C29H32O13
CAS number
33419-42-0
IUPAC name
(1,3-dioxobenzo[de]isoquinolin-2-yl) diethyl phosphate
State
State

At room temperature, etoposide is a solid crystalline substance. It is usually stored as a powder and is typically dissolved in a solvent for pharmaceutical applications.

Melting point (Celsius)
234.50
Melting point (Kelvin)
507.65
Boiling point (Celsius)
524.90
Boiling point (Kelvin)
798.05
General information
Molecular weight
588.57g/mol
Molar mass
588.5670g/mol
Density
1.1980g/cm3
Appearence

Etoposide is a white to yellowish crystalline powder, known for its high purity levels. It lacks any significant odor and its crystalline structure contributes to its relative stability.

Comment on solubility

Solubility Characteristics of (1,3-Dioxobenzo[de]isoquinolin-2-yl) Diethyl Phosphate

The solubility of (1,3-Dioxobenzo[de]isoquinolin-2-yl) diethyl phosphate can be considered an intriguing aspect of its chemical profile. While specific solubility data for this compound may not always be readily available, we can infer some insights based on its structural characteristics.

Factors Influencing Solubility

Several factors can influence the solubility of this compound:

  • Polarity: The presence of polar functional groups in its structure is likely to enhance its solubility in polar solvents, such as water or alcohols.
  • Hydrophobic Regions: The isoquinoline moiety may introduce hydrophobic characteristics, potentially decreasing solubility in aqueous environments.
  • Interactions: Hydrogen bonding and dipole-dipole interactions with solvent molecules can play a significant role in solubility behavior.

General Observations

In general:

  • Compounds with both hydrophilic and hydrophobic elements may exhibit amphiphilic behavior, leading to complex solubility profiles.
  • If dissolved in polar organic solvents like ethanol or acetone, (1,3-Dioxobenzo[de]isoquinolin-2-yl) diethyl phosphate is more likely to achieve greater solubility compared to water.
  • The compound's behavior in mixed solvent systems can often reveal interesting solubility phenomena that merit further exploration.

Overall, while direct solubility values may be sparse, the structural insights and solvent interactions imply that (1,3-Dioxobenzo[de]isoquinolin-2-yl) diethyl phosphate possesses the potential for diverse solubility behavior, dependent on the chemical environment.

Interesting facts

Interesting Facts about (1,3-Dioxobenzo[de]isoquinolin-2-yl) Diethyl Phosphate

(1,3-Dioxobenzo[de]isoquinolin-2-yl) diethyl phosphate is a fascinating compound that sits at the intersection of organic chemistry and materials science. This compound is particularly interesting due to its complex structure which includes both a heterocyclic aromatic system and a phosphate moiety, leading to a variety of potential applications.

Key Features

  • Versatile Applications: Compounds like this can serve as valuable intermediates in the synthesis of pharmaceuticals and agrochemicals.
  • Biochemical Activity: The presence of the dioxo and isoquinoline structure can exhibit interesting biological activities, making it a candidate for further research.
  • Phosphate Group: The diethyl phosphate part is known for its role in biological systems, particularly in relation to energy transfer and signaling pathways.

Given its unique structural attributes, researchers are exploring how the compound's geometry influences its reactivity and overall functionality. “The magic of chemistry lies in the intricate dance of atoms,” a saying that resonates well in the study of such complex compounds, reminding us of the beauty and challenge that come with the territory in organic synthesis.

Potential Applications

  1. Development of novel pharmaceuticals with improved efficacy.
  2. Exploration in the field of organic photovoltaics.
  3. Use as a biolabel in cellular imaging processes due to its unique optical properties.

In summary, (1,3-Dioxobenzo[de]isoquinolin-2-yl) diethyl phosphate is more than just a chemical entity; it is a window into the vast potential of organic chemistry. With ongoing research, it may soon find its place across various scientific disciplines.

Synonyms
Naftalofos
1491-41-4
Naphthalophos
Maretin
Phtalophos
Rametin
Rawetin
Bayer 25820
N-Hydroxynaphthalimide diethyl phosphate
Naftalofosum
Bayer 9002
BAY 9002
Chemagro B-9002
Bayer S940
S-940
Phtalophos (VAN)
O,O-Diethyl N-hydroxynaphthalimide phosphate
E 9002
Caswell No. 495AA
ENT 25567
ENT-25567
ENT 25,567
N-Hydroxynaphthylimide diethyl phosphate
Naftalofosum [INN-Latin]
B-9002
S 940
EINECS 216-078-6
H5IT2P8H5I
Maretin (TN)
N-Hydroxynaphthalimide diethylphosphate
EPA Pesticide Chemical Code 204100
Naftalofos [USAN:INN:BAN]
NSC 229795
NSC-229795
BRN 1551429
CHEBI:51962
NAPHTHALIMIDE, N-HYDROXY-, DIETHYL PHOSPHATE
AI3-25567
NAFTALOFOS [MI]
BAY-9002
NAFTALOFOS [INN]
NAFTALOFOS [USAN]
NAFTALOFOS [MART.]
1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-((diethoxyphosphinyl)oxy)-
Phosphoric acid, diethyl ester, naphthalimido deriv.
N-(Diethoxyphosphinoyloxy)-1,8-naphthalindicarboximid
Phosphoric acid, diethyl ester, N-naphthalimide deriv.
DTXSID2042193
diethyl naphthalimidooxyphosphonate
E-9002
2-[(Diethoxyphosphinyl)oxy]-1H-benz[de]isoquinoline-1,3(2H)-dione
1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-[(diethoxyphosphinyl)oxy]-
2-[(Diethoxyphosphoryl)oxy]-1H-benzo[de]isoquinoline-1,3(2H)-dione
Naftalofosum (INN-Latin)
NAFTALOFOS (MART.)
2-((DIETHOXYPHOSPHINYL)OXY)-1H-BENZ(DE)ISOQUINOLINE-1,3(2H)-DIONE
2-((diethoxyphosphoryl)oxy)-1H-benzo(de)isoquinoline-1,3(2H)-dione
DTXCID0022193
216-078-6
Bayer S-940
Phosphoric acid, 1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl diethyl ester
1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl diethyl phosphate
UNII-H5IT2P8H5I
(1,3-dioxobenzo[de]isoquinolin-2-yl) diethyl phosphate
Naftalofos (USAN/INN)
MLS006013640
SCHEMBL117809
Naphthalimide, diethyl phosphate
CHEMBL2105556
NSC229795
Phosphoric acid, naphthalimido deriv.
AKOS015896336
Phosphoric acid, N-naphthalimide deriv.
AC-18882
SMR004705125
DB-042970
HY-119516
CS-0068620
NS00024882
Naftalofos, PESTANAL(R), analytical standard
WLN: T666 1A M CVNVJ DOPO&O2&O2
D05108
Q27123040
1H-Benz[de]isoquinoline-1, 2-[(diethoxyphosphinyl)oxy]-
O,O-Diethyl N-hydroxynaphthalimide phosphate, Naphthalophos
2-[(Diethoxyphosphoryl)oxy]-1H-benzo[de]isoquinoline-1,3(2H)-dione #