Skip to main content

Chalcone

ADVERTISEMENT
Identification
Molecular formula
C15H12O
CAS number
94-41-7
IUPAC name
1,3-diphenylprop-2-en-1-one
State
State

Chalcone is in a solid state at room temperature. It is usually supplied in a crystalline form or as a fine powder.

Melting point (Celsius)
55.00
Melting point (Kelvin)
328.15
Boiling point (Celsius)
345.40
Boiling point (Kelvin)
618.55
General information
Molecular weight
208.26g/mol
Molar mass
208.2630g/mol
Density
1.0716g/cm3
Appearence

Chalcone appears as a yellow crystalline solid or powder. It is known for its bright yellow color, which is sometimes more intense under different lighting conditions. The crystals may vary in size and shine.

Comment on solubility

Solubility of 1,3-diphenylprop-2-en-1-one

1,3-diphenylprop-2-en-1-one, also known as chalcone, exhibits interesting solubility characteristics influenced by its molecular structure. Here are some key points regarding its solubility:

  • Solvent Dependent: This compound is generally soluble in organic solvents such as ethanol, acetone, and dichloromethane, making it useful in various organic reactions and applications.
  • Insoluble in Water: Due to its hydrophobic nature attributable to the phenyl groups, 1,3-diphenylprop-2-en-1-one is typically insoluble in water.
  • Polarity Influence: The polarizability of the molecule impacts its solubility; thus, polar aprotic solvents often aid in dissolving this compound more effectively.

In summary, 1,3-diphenylprop-2-en-1-one is predominantly soluble in organic solvents while remaining insoluble in water, making it suitable for a variety of organic syntheses and applications in medicinal chemistry.

Interesting facts

Interesting Facts About 1,3-Diphenylprop-2-en-1-one

1,3-Diphenylprop-2-en-1-one, often referred to as chalcone, is a fascinating compound that serves as a core structure in numerous organic compounds and plays a significant role in synthetic organic chemistry. Below are some intriguing aspects of this compound:

  • Versatile Precursors: Chalcones are often considered versatile building blocks in organic synthesis. They can be transformed into a variety of different compounds, including flavonoids, which are important in various biological processes.
  • Biological Activity: Research has revealed that compounds containing chalcone structures possess numerous biological properties, including antioxidant, anti-inflammatory, and antimicrobial activities. This makes them of particular interest in the field of pharmaceuticals.
  • Natural Sources: Chalcones are not only found in laboratory settings but also occur naturally in certain plants. They contribute to the pigmentation of flowers and fruits, which can serve functions such as attracting pollinators.
  • Contribution to Color: Due to their unique structure, chalcones contribute to the vibrant colors in various plants, which is linked to attracting organisms for pollination, aiding in reproductive processes.
  • Research Opportunities: The study of chalcones continues to open new avenues in medicinal chemistry, with ongoing research into their potential as drugs for treating various diseases, including cancer.

The significance of 1,3-diphenylprop-2-en-1-one extends beyond its simple structure; it represents a crucial intersection between natural products and synthetic chemistry, thus providing a vast realm of possibilities for exploration and discovery.

Synonyms
Cinnamoylbenzene
DTXSID8022531
acetophenone, benzal-
1,3-diphenyl-propenone
CHEMBL4777263
HMS3371J11
1,3-di-phenyl-prop-2-en-1-one
NCI60_001320
SY059041
SY233773