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Estradiol

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Identification
Molecular formula
C18H24O2
CAS number
50-28-2
IUPAC name
13-methyl-1,2,3,6,7,8,9,10,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol
State
State

At room temperature, estradiol is in a solid state, specifically as a crystalline powder that is stable under good storage conditions.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.00
Boiling point (Celsius)
433.00
Boiling point (Kelvin)
706.00
General information
Molecular weight
272.38g/mol
Molar mass
272.3830g/mol
Density
1.1690g/cm3
Appearence

Estradiol is a white to creamy white, crystalline powder. It is odorless and stable under ordinary conditions of use and storage.

Comment on solubility

Solubility of 13-methyl-1,2,3,6,7,8,9,10,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol (C18H24O2)

The solubility of 13-methyl-1,2,3,6,7,8,9,10,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol is an intriguing topic, as it can exhibit varied behavior depending on the solvent environment. Here are some key points regarding its solubility:

  • Polarity: Due to the presence of hydroxyl groups (-OH), this compound displays a degree of polarity, making it more soluble in polar solvents.
  • Organic Solvents: It is generally more soluble in organic solvents, such as ethanol and methanol, where the interaction between the solute and solvent is favorable.
  • Aqueous Solubility: Water solubility might be limited due to the overarching non-polar hydrocarbon framework, leading to lower solubility in aqueous environments.

Therefore, one can summarize that while it shows some solubility in polar solvents, its overall solubility profile is complex and influenced by various factors such as temperature and solvent type. Understanding these nuances is essential for applications involving this compound, as “solubility is key to reactivity.”

Interesting facts

Interesting Facts about 13-methyl-1,2,3,6,7,8,9,10,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol

This fascinating compound belongs to the class of natural steroids, which have garnered considerable attention due to their diverse biological activities. Its structure represents a complex hydrocarbon framework, distinctively featuring multiple fused rings that contribute to its unique properties and reactivity.

  • Structural Complexity: The compound exhibits a unique arrangement of atoms that includes a bicyclic structure and several stereocenters, leading to stereoisomerism. This bilateral symmetry can influence its biological behavior.
  • Functionality: The presence of hydroxyl (–OH) groups contributes to its potential as a hormone-like agent in various biological processes, including metabolism and growth regulation.
  • Natural Sources: Compounds similar to this one are often isolated from plants and fungi, suggesting a role in signaling pathways or defense mechanisms within these organisms.
  • Research Applications: Due to its structural features, scientists are exploring its potential in drug development, particularly in fields like oncology, where steroidal compounds are known for their therapeutic effects.

“The complex beauty of steroid chemistry reminds us of the intricate relationships in nature, and how minor structural changes can yield significant variations in biological activity.”

In summary, the compound is not only a striking representation of steroidal structures but also presents a multitude of avenues for academic exploration and practical application in pharmaceutical sciences. Its synthesis and functional analysis are topics of ongoing research, making it a noteworthy subject for anyone interested in organic chemistry and biochemistry.

Synonyms
DEMETRIC ACID
11012-90-1
DTXSID901017063
Estren
AKOS015963315
AC-19326