Skip to main content

Estrone sulfate

ADVERTISEMENT
Identification
Molecular formula
C18H22O5S
CAS number
438-67-5
IUPAC name
(13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) hydrogen sulfate
State
State

Estrone sulfate is generally in a solid state at room temperature, indicative of its molecular stability and compact structural arrangement. This solid form is typical for steroid derivatives and compounds with sulfate groups.

Melting point (Celsius)
254.00
Melting point (Kelvin)
527.00
Boiling point (Celsius)
577.20
Boiling point (Kelvin)
850.20
General information
Molecular weight
350.47g/mol
Molar mass
350.4730g/mol
Density
1.2800g/cm3
Appearence

Estrone sulfate typically appears as a white to off-white crystalline powder. As an organic sodium salt, it should be handled with care to prevent contamination or decomposition. Its crystalline nature reflects the structured arrangement of the molecules within the compound.

Comment on solubility

Solubility Overview

The solubility of (13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) hydrogen sulfate is quite fascinating due to its complex structure.

Factors Affecting Solubility

Several factors influence the solubility of this compound:

  • Polarity: The presence of the hydrogen sulfate group generally increases the compound's polarity, thereby enhancing its solubility in polar solvents such as water.
  • Temperature: Like many compounds, solubility might increase with temperature, which is important to consider during practical applications.
  • Hydrogen Bonding: The compound's ability to form hydrogen bonds with water molecules contributes significantly to its solubility.

Solubility Behavior

In practical scenarios, it is critical to note the following regarding solubility:

  • This compound is expected to be more soluble in aqueous solutions due to the hydrophilic nature of the hydrogen sulfate group.
  • Solubility might be relatively low in non-polar solvents, reflecting the hydrophobic portions of the molecule.
  • Understanding the compound's solubility can help predict its behavior in biological or industrial applications.

In conclusion, while the solubility of (13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) hydrogen sulfate can present a challenge due to its complex structure, its interaction with polar solvents reveals intriguing possibilities for its application across various fields.

Interesting facts

Interesting Facts about 13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl Hydrogen Sulfate

The compound 13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl hydrogen sulfate is a fascinating chemical that showcases the complexity of organic chemistry. Here are some intriguing aspects of this compound:

  • Biomedical Applications: The structure of this compound suggests that it may interact with various biological systems, potentially aiding in drug development for specific medical conditions.
  • Structural Features: The molecule contains a unique polycyclic structure which is characteristic of many naturally occurring steroids, contributing to its biological activity.
  • Natural Occurrence: Similar structural motifs are often found in steroids and hormones, which are crucial for numerous physiological processes in living organisms.
  • Sulfate Group: The presence of the sulfate group not only impacts the compound's reactivity but also plays a role in solubility and interaction with biological targets, which is vital for drug design.
  • Potential Research: Scientists may explore its structural analogs to enhance our understanding of enzyme interactions and mechanisms by which steroid-like compounds exert their effects.

In conclusion, 13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl hydrogen sulfate is not just a simple chemical entity; it embodies the interplay between structure and function that is essential in the field of medicinal chemistry. As noted by researchers, “The intricate architecture of steroid molecules can lead to diverse biological activities”, highlighting the significance of such compounds in ongoing scientific exploration.

Synonyms
SCHEMBL20164989
DTXSID90860094
NS00002422
17-Oxoestra-1(10),2,4,7-tetraen-3-yl hydrogen sulfate