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Strychnine

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Identification
Molecular formula
C21H22N2O2
CAS number
57-24-9
IUPAC name
13,15-dimethyl-11-oxa-15-azatetracyclo[8.8.0.02,7.012,17]octadeca-1(10),2,4,6,8-pentaen-12-ol
State
State

At room temperature, strychnine is a solid. It is typically encountered as a crystalline solid or a powder, which is stable under normal conditions.

Melting point (Celsius)
268.00
Melting point (Kelvin)
541.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
334.42g/mol
Molar mass
334.4170g/mol
Density
1.3680g/cm3
Appearence

Strychnine is a colorless, crystalline alkaloid with a bitter taste. It is often found in its natural form as white crystals or a white crystalline powder. Under certain conditions, it can appear as colorless prismatic crystals.

Comment on solubility

Solubility of 13,15-dimethyl-11-oxa-15-azatetracyclo[8.8.0.02,7.012,17]octadeca-1(10),2,4,6,8-pentaen-12-ol

The solubility of 13,15-dimethyl-11-oxa-15-azatetracyclo[8.8.0.02,7.012,17]octadeca-1(10),2,4,6,8-pentaen-12-ol can be complex, influenced by its unique structural characteristics and presence of functional groups. Here are some key points to consider:

  • Polarity: The compound contains polar functionalities due to the -OH group and the nitrogen atom, which can interact favorably with polar solvents like water.
  • Solvent Interactions: It is likely to have limited solubility in non-polar solvents owing to its polar nature. For example, solvents such as methanol or ethanol may enhance solubility compared to hydrocarbons.
  • Structure-Activity Relationship: The bicyclic and tetracyclic structures may introduce steric hindrance, further affecting solubility in various mediums.
  • Temperature Effects: Solubility may improve with an increase in temperature, which can increase molecular motion and interaction with the solvent.

In summary, understanding the solubility profile is essential for applications involving this compound, particularly in drug formulation and delivery systems. Thus, evaluating its solubility in various solvents and conditions will offer valuable insights into its practical applications.

Interesting facts

Interesting Facts about 13,15-Dimethyl-11-Oxa-15-Azatetracyclo[8.8.0.02,7.012,17]octadeca-1(10),2,4,6,8-pentaen-12-ol

This fascinating compound, known as a complex polycyclic structure, is an excellent example of the **diversity and complexity** found in organic chemistry. Its unique structure is characterized by:

  • Polycyclic Framework: The tetracyclic structure allows for multiple functional groups to interact within a confined space, facilitating intricate chemical behaviors.
  • Presence of Oxygen and Nitrogen: The incorporation of an oxygen atom and a nitrogen atom within the ring system contributes to various reactive centers, making it a potential candidate for organic reactions.
  • Pentaene Configuration: The multiple double bonds in the pentaenyl portion can participate in **conjugation**, which often enhances the stability and reactivity of the compound.

One particularly intriguing aspect of this compound is its potential biological activity. Compounds with similar structures have been investigated for their **antimicrobial properties**. In the realm of drug discovery, understanding the mechanisms and interactions at play within such polycyclic entities can lead to advancements in medicinal chemistry.

Moreover, the **stereochemical considerations** based on its structural arrangement can lead to fascinating insights into isomerism, which can influence the physical properties and biological activity of this compound. A quote that embodies the essence of studying such compounds is: "The beauty of chemistry lies in the endless possibilities inherent in molecular structures."

In summary, 13,15-dimethyl-11-oxa-15-azatetracyclo[8.8.0.02,7.012,17]octadeca-1(10),2,4,6,8-pentaen-12-ol exemplifies the complexities and potential applications of organics in various scientific fields, making it a compelling subject of study for both chemists and biologists alike.

Synonyms
NARANOL
Naranol [INN]
22292-91-7
752168P7XM
8,9,10,11,11a,12-Hexahydro-8,10-dimethyl-7aH-naphtho[1',2':5,6]pyrano[3,2-c]pyridin-7a-ol
UNII-752168P7XM
SCHEMBL351384
CHEMBL2111035
DTXSID50865040
NS00125103
Q6965371
7AH-NAPHTHO(1',2':5,6)PYRANO(3,2-C)PYRIDIN-7A-OL, 8,9,10,11,11A,12-HEXAHYDRO-8,10-DIMETHYL-
8,10-Dimethyl-8,9,10,11,11a,12-hexahydro-7aH-naphtho[1',2':5,6]pyrano[3,2-c]pyridin-7a-ol
8,9,10,11,11A,12-HEXAHYDRO-8,10-DIMETHYL-7AH-NAPHTHO(1',2':5:6)PYRANO(3,2-C)PYRIDIN-7A-OL