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1,3,3-trimethyl-2-methyleneindoline

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Identification
Molecular formula
C13H17N
CAS number
118-12-7
IUPAC name
1,3,3-trimethyl-2-methylene-indoline
State
State

1,3,3-Trimethyl-2-methyleneindoline is a liquid at room temperature.

Melting point (Celsius)
-2.00
Melting point (Kelvin)
271.15
Boiling point (Celsius)
261.00
Boiling point (Kelvin)
534.15
General information
Molecular weight
185.28g/mol
Molar mass
185.2790g/mol
Density
1.0360g/cm3
Appearence

1,3,3-Trimethyl-2-methyleneindoline appears as a pale yellow or colorless liquid. It is often used as an intermediate in the synthesis of dyes and other organic compounds.

Comment on solubility

Solubility of 1,3,3-trimethyl-2-methylene-indoline

1,3,3-trimethyl-2-methylene-indoline is a compound that showcases intriguing solubility characteristics. Understanding its solubility can be approached through several key factors:

  • Polarity: The polarity of the compound significantly influences its solubility in various solvents. Due to its indoline structure, which comprises an aromatic ring, this compound tends to be more non-polar.
  • Solvent Interactions: As a result of its non-polar characteristics, 1,3,3-trimethyl-2-methylene-indoline typically exhibits better solubility in non-polar solvents such as toluene or hexane, rather than in polar solvents like water.
  • Temperature Dependency: Additionally, the solubility may vary with temperature. Generally, an increase in temperature can enhance the solubility of organic compounds.
  • Concentration: The concentration of the compound in the solvent can also impact solubility. A saturated solution can often be reached where no more solute can dissolve in the solvent.

In summary, the solubility of 1,3,3-trimethyl-2-methylene-indoline is primarily influenced by its non-polar nature, leading to better interactions with non-polar solvents. Thus, when considering practical applications or experimental setups involving this compound, it is essential to account for these solubility properties to optimize performance and outcomes.

Interesting facts

Interesting Facts about 1,3,3-trimethyl-2-methylene-indoline

1,3,3-trimethyl-2-methylene-indoline is a fascinating compound with several noteworthy properties and applications that intrigue scientists and students alike. Here are some key points to consider:

  • Structure and Reactivity: The compound features a unique indoline structure, characterized by a fused indole and a saturated nitrogen-containing ring. This particular configuration offers interesting reactivity, especially in organic synthesis and medicinal chemistry.
  • Synthetic Applications: It is often utilized as a versatile building block in organic synthesis, especially in the creation of novel pharmaceuticals and agrochemicals. It demonstrates potential in developing biologically active compounds.
  • Research Significance: Studies have shown that derivatives of this compound possess significant biological activities, including antitumor and antimicrobial properties, which makes it a subject of ongoing research in medicinal chemistry.
  • Color and Light Absorption: Compounds of this family often exhibit unique color properties, which can lead to interesting applications in dyes and pigments. The structure of 1,3,3-trimethyl-2-methylene-indoline allows it to absorb certain wavelengths of light effectively.

"The uniqueness of 1,3,3-trimethyl-2-methylene-indoline lies in its potential to unlock new pathways in chemical synthesis and drug discovery."

Overall, 1,3,3-trimethyl-2-methylene-indoline showcases the intersection of accessible synthetic chemistry and profound biological interest, continuously captivating chemists and researchers exploring its potential. The ongoing studies into its derivatives promise to enhance our understanding of indole-based compounds further.

Synonyms
1,3,3-Trimethyl-2-methyleneindoline
118-12-7
Fischer's base
Fischer base
1H-Indole, 2,3-dihydro-1,3,3-trimethyl-2-methylene-
2-Methylene-1,3,3-trimethylindoline
Fischers Base
Fischer's methylene base
1,3,3-trimethyl-2-methylideneindole
NSC 66176
CCRIS 6608
Indoline, 1,3,3-trimethyl-2-methylene-
EINECS 204-235-1
BRN 0131162
Indoline, 2-methylene-1,3,3-trimethyl-
DTXSID8051596
1,3,3-trimethyl-2-methyleneindole
1,3-Dihydro-1,3,3-trimethyl-2-methyleneindoline
5-20-07-00141 (Beilstein Handbook Reference)
NSC-66176
1,3,3-trimethyl-2-methylidene-2,3-dihydro-1H-indole
MFCD00005813
1,3,3-trimethyl-2-methylene-indoline
Indoline,3,3-trimethyl-
TW7F4XW78N
SCHEMBL918366
SCHEMBL8397425
DTXCID2030148
1,3-Trimethyl-2-methyleneindoline
2-Methylene-1,3-trimethylindoline
NSC66176
STK802332
AKOS000119124
1,3,3-trimethyl-2-methylidene-indole
LS-14079
DB-041390
1,3,3-Trimethyl-2-methyleneindoline, 95%
1,3,3-Trimethyl-2-methyleneindoline, 97%
NS00005231
T0879
WLN: T56 BNY DHJ B1 CU1 D1 D1
EN300-16764
E78126
A803883
2,3-Dihydro-1,3,3-trimethyl-2-methylene-1H-indole
Z56769766
F0001-0295
Indoline, 1,3,3-trimethyl-2-methylene-(6CI,7CI,8CI)
1,3,3-Trimethyl-2-methyleneindoline, liquid, for paper chromatography, >=96.0%
204-235-1