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1,3,5-Trifluorobenzene

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Identification
Molecular formula
C6H3F3
CAS number
372-38-3
IUPAC name
1,3,5-trifluorobenzene
State
State

1,3,5-Trifluorobenzene is in a liquid state at room temperature. It is typically handled in sealed containers to prevent evaporation due to its volatile nature as a liquid.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
83.00
Boiling point (Kelvin)
356.15
General information
Molecular weight
146.07g/mol
Molar mass
146.0670g/mol
Density
1.2800g/cm3
Appearence

1,3,5-Trifluorobenzene is a clear, colorless liquid at room temperature. It is typically transparent and without any visible impurities. As with many other benzene derivatives, it has a distinct aromatic smell which is typical of aromatic hydrocarbons.

Comment on solubility

Solubility of 1,3,5-Trifluorobenzene

1,3,5-Trifluorobenzene (C6H3F3) exhibits some intriguing solubility characteristics owing to the presence of its fluorine atoms. Here are some important points to consider:

  • Polarity: The fluorine atoms contribute to the overall polarity of the molecule, affecting its interactions with solvents.
  • Solvent Compatibility: 1,3,5-Trifluorobenzene is generally more soluble in organic solvents such as hexane and ether compared to polar solvents like water.
  • Aromatic Nature: Being an aromatic compound, it tends to be insoluble in water, which aligns with the general trend observed in non-polar aromatic compounds.

In summary, the solubility of 1,3,5-trifluorobenzene can be described as:

  1. Readily soluble in non-polar solvents.
  2. Poorly soluble in polar solvents like water.
  3. Showing limited solubility due to the hydrophobic character of the aromatic ring.

Thus, while it demonstrates some level of solubility in various organic solvents, its overall behavior aligns with that of typical aromatic compounds, highlighting its distinct solubility profile.

Interesting facts

Interesting Facts about 1,3,5-Trifluorobenzene

1,3,5-Trifluorobenzene, a derivative of benzene, is an intriguing compound with unique properties making it noteworthy in the field of chemistry. Here are some fascinating aspects:

Chemical Structure and Characteristics

  • Substituted Aromatic Compound: This compound features three fluorine atoms substituting hydrogen atoms on the benzene ring, specifically at the 1, 3, and 5 positions. This symmetrical substitution contributes to its distinct chemical behavior.
  • Fluorine Influence: The presence of fluorine atoms enhances the reactivity of the compound, affecting its interactions with various reagents and solvents, which can lead to interesting pathways in synthetic chemistry.

Applications and Uses

  • Solvent: 1,3,5-Trifluorobenzene is often used as a solvent in chemical reactions due to its unique chemical properties, especially in reactions involving sensitive functional groups.
  • Intermediate in Synthesis: This compound serves as a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals, playing a crucial role in developing new compounds.

Environmental and Safety Considerations

While 1,3,5-trifluorobenzene has valuable applications, it’s essential to consider environmental and safety factors:

  • Toxicity: Caution is advised when handling this compound, as it poses certain toxic risks. Safety protocols should always be in place to minimize exposure.
  • Environmental Impact: Like many fluorinated compounds, it can persist in the environment, raising concerns about its long-term effects.

In summary, 1,3,5-trifluorobenzene exemplifies how structural modifications can lead to exciting new properties and applications in the realm of chemical science. Its role as a versatile chemical building block exemplifies the ongoing innovation in organic synthesis and material science.

Synonyms
1,3,5-TRIFLUOROBENZENE
372-38-3
sym-Trifluorobenzene
Benzene, 1,3,5-trifluoro-
UNII-BN94C411F8
BN94C411F8
EINECS 206-751-2
MFCD00000333
NSC-10264
DTXSID90190686
NSC 10264
1,3,5-TRIFLUORO BENZENE
1,5-Trifluorobenzene
1,3,5-trifluorbenzol
Benzene,3,5-trifluoro-
1,3,5-tri-fluorobenzene
1,3,5-Trifluorobenzene #
SCHEMBL449836
1,3,5-Trifluorobenzene, 97%
DTXCID30113177
NSC10264
XH1408
AKOS005258293
FT70543
PS-10252
NS00041741
T1039
EN300-25659
Q27274766
206-751-2