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1,4-Difluorobenzene

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Identification
Molecular formula
C6H4F2
CAS number
540-36-3
IUPAC name
1,4-difluorobenzene
State
State

At room temperature, 1,4-Difluorobenzene is found in a liquid state.

Melting point (Celsius)
-18.00
Melting point (Kelvin)
255.20
Boiling point (Celsius)
85.60
Boiling point (Kelvin)
358.80
General information
Molecular weight
114.10g/mol
Molar mass
114.1030g/mol
Density
1.1686g/cm3
Appearence

1,4-Difluorobenzene is a colorless liquid. It is known for its aromatic odor, similar to other benzene derivatives. Due to its nature, it is often handled within laboratory settings using appropriate safety measures.

Comment on solubility

Solubility of 1,4-Difluorobenzene

1,4-Difluorobenzene, with the chemical formula C6H4F2, exhibits some interesting solubility characteristics. This compound is primarily characterized as a *non-polar* solvent due to its symmetrical structure and the influence of the fluorine substituents. Here are some key points regarding its solubility:

  • Solubility in Water: 1,4-Difluorobenzene is insoluble in water. The high electronegativity of fluorine and the non-polar characteristics of the benzene ring limit its interaction with polar water molecules.
  • Solubility in Organic Solvents: It is more soluble in organic solvents such as ethanol, acetone, and other hydrocarbons, which are also non-polar or only weakly polar. This property makes it useful in organic chemistry applications.
  • Temperature Effects: The solubility can vary with temperature. Generally, increased temperatures can lead to increased solubility in organic solvents, though the effects in water remain negligible.
  • Applications: Its solubility behavior is important when considering its use in various applications, including as a solvent in chemical reactions and synthesis.

In summary, 1,4-difluorobenzene's solubility is dominated by its non-polar nature, making it incompatible with polar solvents, particularly water. As a practical takeaway, always consider the polarity of solvents when working with such compounds to ensure the desired reaction conditions.

Interesting facts

Interesting Facts about 1,4-Difluorobenzene

1,4-Difluorobenzene, also known as para-difluorobenzene, is an intriguing organic compound with distinct characteristics and applications in the field of chemistry. This aromatic compound consists of a benzene ring with two fluorine atoms located at the 1 and 4 positions, contributing significantly to its chemical properties.

Chemical Structure and Properties

  • Conjugated System: The compound features a highly stable conjugated system due to the presence of alternating single and double bonds in the benzene ring. This stability results in a relatively inert behavior in many chemical environments.
  • Electronegativity Influence: The fluorine atoms, being highly electronegative, impart unique electronic and steric effects to the benzene ring. This can make 1,4-difluorobenzene an interesting substrate for various chemical reactions.

Applications

  • Synthesis Intermediates: 1,4-Difluorobenzene serves as a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals, aiding in the development of new compounds.
  • Organic Electronics: Its unique electronic properties allow for potential applications in the field of organic electronics, particularly in organic light-emitting diodes (OLEDs) and organic photovoltaic devices.

Health and Safety Considerations

As with many fluorinated compounds, it’s essential to handle 1,4-difluorobenzene with caution. The compound may pose potential health risks, including:

  • Inhalation Risks: Exposure to vapors can be harmful, necessitating proper ventilation and protective equipment during handling.
  • Environmental Impact: Care must also be taken regarding its environmental impact, as fluorinated compounds can persist in ecosystems.

In conclusion, 1,4-difluorobenzene is far more than just a simple aromatic compound. Its unique chemical structure, versatile applications, and important safety considerations make it a fascinating subject of study for chemists and students alike.

Synonyms
1,4-DIFLUOROBENZENE
p-Difluorobenzene
2,5-difluorobenzene
1,4-Difluorbenzol
UNII-Y9FQ2EF0Z6
EINECS 208-742-9
Y9FQ2EF0Z6
NSC 10286
CHEBI:38585
NSC-10286
P-DIFLUOROBENZENE [MI]
DTXSID1075432
QUGUFLJIAFISSW-UHFFFAOYSA-
pDifluorobenzene
paraDifluorobenzene
Benzene, pdifluoro
Benzene, 1,4difluoro
Benzene, 1,4difluoro (9CI)
DTXCID0041563
inchi=1/c6h4f2/c7-5-1-2-6(8)4-3-5/h1-4h
qugufljiafissw-uhfffaoysa-n
540-36-3
Benzene, 1,4-difluoro-
para-Difluorobenzene
Benzene, p-difluoro-
MFCD00000344
1,4-Difluoro-benzene
Benzene,4-difluoro-
WLN: FR DF
1,4-bis(fluoranyl)benzene
SCHEMBL13499
CHEMBL496192
1,4-Difluorobenzene, >=99%
NSC10286
AKOS000120883
DS-3203
1,4-Difluorobenzene, analytical standard
DB-020072
DB-052463
D1628
NS00043113
EN300-20356
1,4-Difluorobenzene 2000 microg/mL in Methanol
A829919
Q27117911
F0001-1411