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Sulfasalazine

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Identification
Molecular formula
C10H11N3O3S
CAS number
599-79-1
IUPAC name
[(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)amino]methanesulfonic acid
State
State

Sulfasalazine is typically solid at room temperature.

Melting point (Celsius)
245.00
Melting point (Kelvin)
518.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
300.32g/mol
Molar mass
300.3200g/mol
Density
1.2380g/cm3
Appearence

Sulfasalazine typically appears as a yellow to brownish crystalline powder. It is slightly soluble in water and exhibits a distinct characteristic odor.

Comment on solubility

Solubility of [(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)amino]methanesulfonic acid

The solubility of the compound [(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)amino]methanesulfonic acid can be influenced by several factors, making it an interesting case in the realm of chemical compounds. Typically, the following aspects play a crucial role in determining its solubility:

  • Polarity: This compound contains both polar and non-polar segments. The presence of the sulfonic acid group enhances its solubility in polar solvents, particularly water.
  • pH Levels: The solubility may also vary with changes in pH. As a weak acid, it might show increased solubility in more alkaline solutions.
  • Temperature: Generally, rising temperatures can increase the solubility of solids in liquids; thus, higher temperatures might enhance the dissolution of this compound.

Furthermore, it is important to note that the solubility of chemical compounds often correlates with their molecular structure. In this case, the electron-donating and withdrawing effects of the substituents can considerably affect the overall solubility profile. As a rough rule of thumb,

“Like dissolves like”

holds true, suggesting that the compound will be more soluble in organic solvents that are similar in polarity to its own structure. However, empirical data on the specific solubility of this compound is essential for precise applications and should be conducted under controlled laboratory conditions for accurate results.

Interesting facts

Interesting Facts About [(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)amino]methanesulfonic acid

[(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)amino]methanesulfonic acid is a fascinating compound that presents a myriad of intriguing aspects for scientists and chemistry enthusiasts alike. Here are some key points to consider:

  • Diverse Applications: This compound plays a crucial role in the field of pharmaceuticals, particularly in the development of novel medications. Its unique structure offers potential for various therapeutic applications.
  • Structural Intricacies: The presence of both a pyrazole ring and a sulfonic acid group contributes to the compound's reactive nature. This complexity enables vivid interactions with biological systems.
  • Mechanism of Action: Compounds like this are often studied for their ability to modulate enzyme activity and influence metabolic pathways. Understanding these mechanisms provides invaluable insights into drug design.
  • Inhibition Studies: Research has shown that similar compounds can act as effective inhibitors in various enzymatic reactions, making this compound a candidate worth investigating for enzyme interactions.
  • Property Exploration: The physicochemical properties of this compound, attributed to its functional groups, position it well for studies focused on solubility and stability, which are critical for drug formulation.

The exploration of [(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)amino]methanesulfonic acid is a testament to the creativity and innovative spirit within the field of chemistry. As researchers continue to unveil its potential, we may see exciting developments arise from this intriguing compound. Indeed, as one researcher aptly put it, _"The beauty of chemistry lies in its endless opportunities for discovery."_

Synonyms
Sulfamidopyrine
117-38-4
(Antipyrinylamino)methanesulfonic acid
SULFAMPYRINE
Methanesulfonic acid, (antipyrinylamino)-
Metamizole impurity E [USP-MC]
((1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino)methanesulfonic acid
Sulfamidopyrine [WHO-DD]
727Q94151Q
DTXSID001017066
Methanesulfonic acid, ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)amino)-
Methanesulfonic acid, 1-((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)amino)-
4-N-DESMETHYLMETAMIZOLE [EP IMPURITY]
Metamizole impurity E (USP-MC)
METAMIZOLE SODIUM MONOHYDRATE IMPURITY E [EP IMPURITY]
4-N-DESMETHYLMETAMIZOLE (EP IMPURITY)
METAMIZOLE SODIUM MONOHYDRATE IMPURITY E (EP IMPURITY)
DTXCID40912416
[(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)amino]methanesulfonic acid
[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]methanesulfonic acid
Melaminsulfone
Metamizole EP Impurity E
UNII-727Q94151Q
Metamizole impurity E
starbld0029560
SCHEMBL11061329
IM181685
NS00010503
Q27266032