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Amitriptyline Hydrochloride

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Identification
Molecular formula
C20H24ClN
CAS number
549-18-8
IUPAC name
15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one;hydrochloride
State
State

Under standard conditions, Amitriptyline hydrochloride is a solid. Generally handled in tablet or powder form, it is stable and retains its structure at room temperature.

Melting point (Celsius)
197.00
Melting point (Kelvin)
470.15
Boiling point (Celsius)
515.60
Boiling point (Kelvin)
788.80
General information
Molecular weight
313.87g/mol
Molar mass
313.8650g/mol
Density
0.7260g/cm3
Appearence

Amitriptyline hydrochloride appears as a white or almost white crystalline powder. It is typically odorless and has a bitter taste.

Comment on solubility

Solubility of 15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one; hydrochloride

The solubility of chemical compounds, especially those related to complex structures like 15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one; hydrochloride, can provide significant insights into their potential applications and effectiveness in various environments. Here are some key points about its solubility:

  • Hydrochloride Form: Being in the hydrochloride form typically enhances the solubility of the compound in aqueous solutions due to the formation of ion-dipole interactions with water molecules.
  • Polar Functional Groups: The presence of multiple oxygen atoms in the structure suggests a propensity for polar interactions, which usually leads to higher solubility in polar solvents like water.
  • Influence of Structure: The complex bicyclic structure could introduce steric hindrance that might affect solubility negatively or positively depending on the overall balance of hydrophilic and hydrophobic characteristics.

In summary, while several factors influence the solubility of this compound, including its ionic nature due to hydrochloride formation and the presence of polar functional groups, definitive solubility data is essential for precise applications. It remains crucial to perform experimental solubility tests under various conditions to fully understand its potential.

Interesting facts

Interesting Facts about 15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one; hydrochloride

This fascinating compound, with a complex name and structure, plays a significant role in various fields of scientific research. Here are some intriguing aspects to consider:

  • Diverse Applications: Due to its multi-functional characteristics, this compound has potential applications in medicinal chemistry, particularly in developing therapeutic agents.
  • Structural Complexity: The intricate arrangement of its functional groups and rings makes the compound a subject of interest in the study of organic chemistry and molecular design.
  • Pharmacological Potential: Compounds of this nature often exhibit unique biological activities, which can include anti-inflammatory, anti-cancer, and antiviral properties.
  • Research Interest: The unique structural attributes of this compound position it as a valuable target for synthetic chemists seeking new pathways to create novel drugs.
  • Hydrochloride Form: The presence of the hydrochloride form enhances its stability and solubility, making it more suitable for various laboratory applications.

As the landscape of chemical research continues to evolve, compounds like 15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one; hydrochloride remind us of the boundless possibilities within molecular design and its potential impact on future scientific discoveries. The intricate interplay of its structural components can lead to groundbreaking advancements in health and materials science.

Synonyms
PROTOPINE HYDROCHLORIDE
6164-47-2
Protopine HCl
HSDB 3556
EINECS 228-196-5
NSC 11440
UNII-96481YJ70G
NSC-11440
96481YJ70G
7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride
Bis(1,3)benzodioxolo(4,5-C:5',6'-g)azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-, hydrochloride
DTXSID70210654
PROTOPINE HYDROCHLORIDE [MI]
BIS(1,3)BENZODIOXOLO(4,5-C:5',6'-G)AZECIN-13(5H)-ONE, 4,6,7,14-TETRAHYDRO-5-METHYL-, HYDROCHLORIDE (1:1)
5,6,8,14-tetrahydro-14a-hydroxy-7-methyl-1,3-benzodioxolo(5,6-a)-1,3-benzodioxolo(4,5-g)quinolizinium chloride
5,6,8,14-tetrahydro-14a-hydroxy-7-methyl-1,3-benzodioxolo[5,6-a]-1,3-benzodioxolo[4,5-g]quinolizinium chloride
Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-, hydrochloride (1:1)
DTXCID00133145
7,13aSecoberbin13aone, 7methyl2,3:9,10bis(methylenedioxy), hydrochloride
7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride (8CI)
228-196-5
Bis(1,3)benzodioxolo(4,5-c:5',6'-g)azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-, hydrochloride (9CI)
Bis(1,3)benzodioxolo(4,5c:5',6'g)azecin13(5H)one, 4,6,7,14tetrahydro5methyl, hydrochloride
Protopine (hydrochloride)
NSC11440
15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one;hydrochloride
ARGEMONINE (PROTOPINE
SCHEMBL4456077
CHEMBL2165579
HY-N0793A
NWNVDSJZGYDVQW-UHFFFAOYSA-N
MFCD00236406
AKOS040760082
FS-9817
Protopine hydrochloride, >=98%, solid
DA-77171
CS-0084037
NS00080865
Q27271857
7, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride
Bis[1,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-, hydrochloride