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Monensin

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Identification
Molecular formula
C36H62O11
CAS number
17090-79-8
IUPAC name
16-[3-(2,4-dihydroxy-6-isopropyl-5-methyl-tetrahydropyran-2-yl)-2-hydroxy-1-methyl-butyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one
State
State

At room temperature, Monensin is typically found in the solid state, appearing as a powder.

Melting point (Celsius)
103.00
Melting point (Kelvin)
376.15
Boiling point (Celsius)
132.00
Boiling point (Kelvin)
405.15
General information
Molecular weight
671.87g/mol
Molar mass
671.8700g/mol
Density
1.2909g/cm3
Appearence

Monensin is a solid substance that can appear as a white to beige powder. It is typically odorless or may have a very faint specific odor.

Comment on solubility

Solubility of 16-[3-(2,4-dihydroxy-6-isopropyl-5-methyl-tetrahydropyran-2-yl)-2-hydroxy-1-methyl-butyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one (C36H62O11)

The solubility of this complex organic compound can be influenced by several factors, given its unique structure and functional groups. Generally, the solubility of such molecules can be assessed based on the following aspects:

  • Polarity: The presence of multiple hydroxyl (-OH) groups often enhances the polarity of the molecule, which can facilitate solubility in polar solvents such as water.
  • Hydrophobic regions: The isopropyl and methyl groups create hydrophobic regions that may impede solubility in highly polar solvents while promoting solubility in organic solvents like ethanol or acetone.
  • Hydrogen bonding: The ability of the compound to form hydrogen bonds with solvent molecules can significantly influence dissolution. More hydrogen bonding leads to better solubility in polar solvents.
  • Temperature: Increased temperature typically enhances solubility, particularly for organic compounds, which may dissolve better in heated conditions.

In summary, the solubility of C36H62O11 likely shows a dual nature: it may be soluble in polar solvents to a degree, yet is expected to have greater solubility in non-polar organic solvents due to its hydrophobic characteristics. Therefore, careful consideration of solvent choice is crucial for achieving successful dissolution.

Interesting facts

Interesting Facts about 16-[3-(2,4-dihydroxy-6-isopropyl-5-methyl-tetrahydropyran-2-yl)-2-hydroxy-1-methyl-butyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one

This compound, with a notably complex structure, showcases the incredible diversity in organic chemistry. Here are some fascinating insights into its properties and potential applications:

  • Natural Product Potential: Compounds with similar skeletal frameworks are often found in nature, suggesting potential biological activity. This compound may serve as a lead for discovering new pharmaceuticals or nutraceuticals.
  • Functional Groups: The presence of multiple hydroxyl (–OH) groups hints at possible interactions with biological systems. These functionalities often enhance solubility and reactivity, making the compound a candidate for various applications in medicinal chemistry.
  • Stereochemistry: The intricate arrangement of the isopropyl and methyl groups may lead to unique stereochemical outcomes, which can be critical in determining the compound's efficacy in biological contexts.
  • Application in Drug Design: The compound's structure allows for interactions with various biomolecules, potentially influencing cell signaling pathways. Researchers may explore its use in drug design, especially in targeting specific receptors or enzymes.

As noted by renowned chemist Linus Pauling, "the best way to have a good idea is to have lots of ideas." The intricate nature of this compound exemplifies how complex interactions in molecular structures can lead to innovative scientific breakthroughs. Further research could unlock secrets to this compound's significance in pharmacology and beyond.

In addition, the overall structure reminds us that natural products often hold the key to understanding and solving complex biological challenges. We stand at the forefront of discovery, exploring the rich potential held within this fascinating chemical compound.

Synonyms
bafilomycin A1
88899-55-2
16-[4-(2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl)-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one
NCI60_003625
SY078075
NS00011695
16-[4-(2,4-dihydroxy-6-isopropyl-5-methyloxan-2-yl)-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one