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Adriamycin

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Identification
Molecular formula
C27H29NO11
CAS number
57-77-0
IUPAC name
1,6-bis(2-chloroethylamino)hexane-2,3,4,5-tetrol
State
State

Adriamycin at room temperature is typically available as a solid in its purified form. It must be handled with care, as it can be sensitive to environmental factors like humidity and temperature. The compound is stored in tightly closed containers to maintain stability and prevent degradation.

Melting point (Celsius)
195.50
Melting point (Kelvin)
468.70
Boiling point (Celsius)
352.05
Boiling point (Kelvin)
625.20
General information
Molecular weight
595.55g/mol
Molar mass
595.3290g/mol
Density
1.3004g/cm3
Appearence

Adriamycin appears as a red to orange crystalline powder. It is often supplied in solid form and slowly changes color upon exposure to light and air. The compound is soluble in water and organic solvents, which gives it versatility in various chemical and pharmaceutical applications. Impurities and degradation products can cause variations in its pure form color.

Comment on solubility

Solubility of 1,6-bis(2-chloroethylamino)hexane-2,3,4,5-tetrol

The solubility of 1,6-bis(2-chloroethylamino)hexane-2,3,4,5-tetrol can be impacted by several factors, including its molecular structure and functional groups. This compound contains both hydrophilic and hydrophobic components, which play a significant role in its solubility properties.

Key Points About Its Solubility:

  • Hydrophilic Nature: The presence of multiple hydroxyl groups (–OH) in the tetrol portion makes the compound more likely to be soluble in polar solvents such as water.
  • Hydrophobic Interactions: The chloroethylamino groups may introduce some hydrophobic characteristics which could limit solubility in highly polar solvents.
  • Potential Solubility in Organic Solvents: The compound may also exhibit solubility in certain organic solvents, which could accommodate the hydrophobic regions more effectively.

In general, the solubility of such a compound can be described as moderate but varies significantly depending on the solvent medium. It emphasizes the importance of considering both structural features and external conditions when predicting solubility. As with many complex compounds, “the whole can be different from the sum of its parts” when applying traditional solubility rules.

Interesting facts

Interesting Facts about 1,6-bis(2-chloroethylamino)hexane-2,3,4,5-tetrol

1,6-bis(2-chloroethylamino)hexane-2,3,4,5-tetrol is a fascinating compound primarily recognized for its role in medicinal chemistry and potential therapeutic applications. Here are some intriguing aspects of this compound:

  • Medicinal Importance: This compound is a derivative sometimes utilized in the synthesis of pharmaceuticals, particularly in the development of anticancer agents.
  • Design and Structure: The presence of multiple amine groups allows it to participate in various chemical reactions, making it an interesting subject for research into drug formulation.
  • Mechanism of Action: Its structure suggests that it can act as a bioactive molecule, potentially interacting with biological targets such as DNA or specific enzymes.
  • Chlorine Atoms: The chlorinated ethylamine groups contribute to its reactivity, opening pathways to explore for creating novel compounds with enhanced activity.
  • Therapeutic Potential: Research continues into its applications, particularly in treating diseases where modulation of DNA and cellular processes is beneficial.

In summary, 1,6-bis(2-chloroethylamino)hexane-2,3,4,5-tetrol presents itself as a compound of notable interest within the realms of organic and medicinal chemistry. Its unique structure and potential roles in pharmaceuticals make it a compelling subject for further exploration and study. As with many compounds, understanding its properties and behaviors could lead to significant advancements in drug discovery and development.

Synonyms
SCHEMBL8196
DTXSID80859497
NS00005532
1,6-Bis[(2-chloroethyl)amino]-1,6-dideoxyhexitol