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Clomiphene

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Identification
Molecular formula
C26H28ClNO
CAS number
50-41-9
IUPAC name
16-chloro-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
State
State
The compound is a solid at room temperature, typically in a crystalline form.
Melting point (Celsius)
116.50
Melting point (Kelvin)
389.65
Boiling point (Celsius)
559.30
Boiling point (Kelvin)
832.45
General information
Molecular weight
405.97g/mol
Molar mass
405.9660g/mol
Density
1.2000g/cm3
Appearence

Clomiphene appears as a white to pale yellow crystalline powder. It is often observed to be pale yellow when impure or exposed to light. This compound lacks significant odor and is typically crystalline in its pure form.

Comment on solubility

Solubility of 16-chloro-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one

The solubility of 16-chloro-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one is a noteworthy aspect to consider. Given its complex molecular structure, its behavior in solvents can be quite distinctive. Here are some insights:

  • Hydrophobic Characteristics: The presence of multiple hydrocarbon rings and a chlorine atom often results in limited solubility in water. Such compounds are generally more soluble in organic solvents.
  • Solvent Effects: This compound may exhibit better solubility in non-polar solvents like hexane or toluene, while being less soluble in polar solvents such as methanol or water.
  • Temperature Influence: Solubility can also depend on temperature; an increase in temperature often increases solubility in organic solvents.
  • Functional Group Influence: The presence of the chlorine atom can interact with solvents differently, potentially assisting in solubilization in organic media.

In summary, the solubility behavior of this compound is characterized by its preference for organic solvents over aqueous solutions. As a result, understanding its solubility is essential for practical applications, including extraction and formulation in pharmaceuticals and chemical research.

Interesting facts

Interesting Facts About 16-chloro-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one

The compound 16-chloro-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one belongs to a fascinating class of chemical compounds known as steroids. Its complex structure contributes to its unique properties and biological activities.

Key Features

  • Synthetic Origin: This compound is a synthetic derivative, and such modified steroids are often utilized in medical therapies.
  • Biological Activity: The presence of chlorine and methyl groups can enhance the compound's activity, making it valuable in pharmacology.
  • Hormonal Influence: As a steroid, it may impact hormonal functions in organisms, a point of interest for researchers in endocrinology.
  • Analytical Chemistry: The intricate structure presents challenges and opportunities for scientists using advanced techniques like NMR and mass spectrometry to elucidate its properties.

Furthermore, compounds in this structural family are often studied for their potential therapeutic applications. According to some researchers, "understanding the interaction of modified steroids with biological systems can lead to groundbreaking advancements in medication for various diseases." This highlights the significance of compounds like 16-chloro-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one in the broader context of medicinal chemistry.

In addition to its biological aspects, the study of such compounds can inform environmental science, particularly in understanding how synthetic molecules behave in ecosystems. As scientists continue to explore various dimensions of this and similar compounds, their potential applications and implications are becoming increasingly clear.

Synonyms
20377-68-8
DTXSID80942535
16-Chloroestra-1(10),2,4-trien-17-one