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Hexamethylene diisocyanate

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Identification
Molecular formula
C8H12N2O2
CAS number
822-06-0
IUPAC name
1,6-diisocyanatohexane
State
State

Hexamethylene diisocyanate is a liquid at room temperature.

Melting point (Celsius)
-67.00
Melting point (Kelvin)
206.15
Boiling point (Celsius)
251.50
Boiling point (Kelvin)
524.65
General information
Molecular weight
168.21g/mol
Molar mass
168.2090g/mol
Density
1.0530g/cm3
Appearence

Hexamethylene diisocyanate appears as a colorless to pale yellow liquid. It is commonly used in the production of polyurethane products.

Comment on solubility

Solubility of 1,6-Diisocyanatohexane

1,6-Diisocyanatohexane, also known as HDI (hexamethylene diisocyanate), exhibits interesting solubility characteristics that are crucial to its applications in various industrial fields. When discussing its solubility, it is important to consider the following factors:

  • Polar vs. Nonpolar Solvents: 1,6-Diisocyanatohexane is significantly soluble in polar organic solvents such as acetone, ethyl acetate, and dimethylformamide (DMF). This solubility is attributed to its polar isocyanate groups, which can engage in hydrogen bonding and dipole interactions.
  • Poor Solubility in Water: This compound is insoluble in water due to its hydrophobic alkane chain that repels water molecules, making it incompatible with aqueous environments.
  • Implications for Use: The solubility profiles allow for its use in producing coatings, adhesives, and foams where interaction with other organic components is essential.

In summary, the solubility of 1,6-diisocyanatohexane in polar solvents while remaining insoluble in water highlights its versatility and importance in synthetic applications.

Interesting facts

Interesting Facts about 1,6-Diisocyanatohexane

1,6-Diisocyanatohexane, commonly known as HDI (Hexamethylene diisocyanate), is a fascinating compound in the realm of organic chemistry and industrial applications. Here are some engaging insights into this versatile chemical:

  • Versatile Building Block: 1,6-Diisocyanatohexane serves as a key component in the production of polyurethanes, which are used in a myriad of applications such as coatings, adhesives, and foams.
  • Predictable Reactivity: The diisocyanate features two isocyanate groups, which allow it to easily react with polyols to form polymers, enabling the customization of material properties.
  • Emission Control: In the context of industrial use, HDI is valued for its ability to produce low-VOC (volatile organic compound) coatings, making it a more environmentally friendly option in comparison to some other isocyanates.
  • Safe Handling: While 1,6-Diisocyanatohexane can pose health risks (such as respiratory issues and skin sensitization), advancements in industrial practices have led to better safety protocols to mitigate exposure.
  • Applications Beyond Coatings: Beyond cosmetics and construction, this compound is also used in the automotive industry for manufacturing durable and lightweight materials, illustrating its broad range of utility.

As researchers continue to explore new formulations and processes, 1,6-Diisocyanatohexane remains a crucial player in the development of advanced materials, showcasing the ingenuity and adaptability of modern chemistry.

Synonyms
1,6-Diisocyanatohexane
HEXAMETHYLENE DIISOCYANATE
822-06-0
1,6-Hexamethylene diisocyanate
Hexane, 1,6-diisocyanato-
hexamethylenediisocyanate
CHEBI:53578
HSDB 6134
Hexamethylene diisocyanate, 1,6-
EINECS 212-485-8
UNII-0I70A3I1UF
BRN 0956709
CCRIS 8431
DTXSID4024143
AI3-28285
NSC-11687
1,6-diisocyanatohexamethylene
DTXCID004143
1,6-hexamethylene di-isocyanate
EC 212-485-8
4-04-00-01349 (Beilstein Handbook Reference)
Desmodur N
HEXAMETHYLENE DIISOCYANATE [HSDB]
Hexamethylene-1,6-diisocyanate [Diisocyanates]
HEXAMETHYLENE-1,6-DIISOCYANATE (DIISOCYANATES)
HDI cpd
1,6diisocyanatohexane
Hexane 1,6diisocyanate
Hexamethylene diisocianate
1,6Hexylene diisocyanate
Hexane, 1,6diisocyanato
Metylenobisfenyloizocyjanian
1,6Hexanediol diisocyanate
Hexamethylene1,6diisocyanate
1,6hexamethylene diisocyanate
Hexamethylene diisocyanic acid
Hexamethylene diisocyanate (ACGIH)
88357-62-4
Isocyanic acid, diester with 1,6hexanediol
1,6-HEXAMETHYLENE DIISOCYANATE [INCI]
1,6-diisocyanatohexane, HDI, hexamethylene-1,6-diisocyanate, 1,6-hexamethylene diisocyanate
11142-52-2
212-485-8
618-151-1
inchi=1/c8h12n2o2/c11-7-9-5-3-1-2-4-6-10-8-12/h1-6h
rramgcgofnqtld-uhfffaoysa-n
Hexane 1,6-diisocyanate
1,6-Hexylene diisocyanate
Hexamethylene-1,6-diisocyanate
1,6-Hexanediol diisocyanate
Isocyanic acid, hexamethylene ester
TL 78
HDI
Szesciometylenodwuizocyjanian
Metyleno-bis-fenyloizocyjanian
MFCD00002047
NSC 11687
Isocyanic acid, diester with 1,6-hexanediol
1,6-diisocyanato-hexane
0I70A3I1UF
Hexamethylene 1,6-diisocyanate
1,6-hexane diisocyanate
53895-37-7
CAS-822-06-0
Hexamethylendiisokyanat [Czech]
Hexamethylendiisokyanat
UN2281
hexamethylene di-isocyanate
Szesciometylenodwuizocyjanian [Polish]
Metyleno-bis-fenyloizocyjanian [Polish]
Desmodur H
Hexane,6-diisocyanato-
1,6-diisocyanato hexane
WLN: OCN6NCO
Epitope ID:115018
Isocyanic acid,6-hexanediol
SCHEMBL15038
OCN-(CH2)6-NCO
1,6-hexamethylene-diisocyanate
1,6-Diisocyanatohexane, 98%
GTPL6291
CHEMBL1896533
HEXANE,1,6-DIISOCYANATE
NSC11687
Tox21_202206
Tox21_300161
STL301890
AKOS000120355
NCGC00164175-01
NCGC00164175-02
NCGC00164175-03
NCGC00254122-01
NCGC00259755-01
PD051392
S 90
S-90
DB-225988
H0324
NS00008899
EN300-20358
Hexamethylene diisocyanate [UN2281] [Poison]
A840272
Q418197
Hexamethylene diisocyanate, purum, >=98.0% (GC)
Hexamethylene diisocyanate, puriss., >=99.0% (GC)