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Oxalidine

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Identification
Molecular formula
C17H25ClN2O2
CAS number
63368-97-8
IUPAC name
16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene;chloride
State
State

At room temperature, Oxalidine is typically found in a solid state characterized by its crystalline structure.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
306.00
Boiling point (Kelvin)
579.15
General information
Molecular weight
308.85g/mol
Molar mass
307.7780g/mol
Density
1.0509g/cm3
Appearence

Oxalidine typically appears as a white crystalline solid. The compound is known for its distinctive structural features and fine crystalline texture.

Comment on solubility

Solubility of 16,17-Dimethoxy-5,7-Dioxa-13-Azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene; Chloride

The solubility of this complex organic compound, 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene; chloride, can be described through a combination of structural and environmental factors:

  • Polarity: Due to the presence of ionic and polar functional groups, the compound is expected to exhibit some degree of solubility in polar solvents such as water.
  • Hydrogen Bonding: The methoxy groups (–OCH3) present in the structure can possibly enhance solubility in polar media by forming hydrogen bonds.
  • Influence of Chloride Ion: The presence of the chloride ion can further increase water solubility since it is a common component that enhances ionic interactions in aqueous solutions.

However, the overall solubility may still be limited by the compound's complex cyclic structure which may hinder full interaction with solvent molecules. In summary:

  1. Expect moderate solubility in polar solvents.
  2. Possible low solubility in non-polar solvents.
  3. Experimentation is essential to determine exact solubility parameters.

Understanding the solubility of such intricate compounds is vital for their practical applications in fields like pharmacology and materials science.

Interesting facts

Interesting Facts about 16,17-Dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene; Chloride

This fascinating compound belongs to a unique class of organic molecules characterized by their intricate cyclic structures and multiple functional groups. Here are several interesting points regarding this complex molecule:

  • Structural Complexity: With its pentacyclic framework and azonia-cationic nature, this compound showcases an impressive array of ring systems that contribute to its chemical diversity.
  • Chemical Applications: Due to its unique structure, this compound may serve as a precursor or functional agent in various synthetic pathways. Its potential utility in medicinal chemistry is particularly exciting, as compounds with similar frameworks often exhibit biological activity.
  • Versatile Reactions: The presence of ether linkages within the structure allows for interesting reactivity and potential interactions with other chemical species, making it a candidate for further exploration in materials science.
  • Research Significance: Studying compounds like this can provide insights into mechanisms of action in biological systems and lead to the discovery of novel therapeutic agents. Their unusual arrangements can inspire new methodologies for synthesis and application.
  • Historical Context: Compounds originating from similar cyclic structures have been used in traditional medicine, illustrating the enduring relationship between complex organic compounds and health.

As you delve into the world of chemistry, you may find that the beauty of compounds such as 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene; chloride lies not just in their applications, but also in the challenge they represent for chemists aiming to unlock their full potential.

Synonyms
berberine chloride
Berberine hydrochloride
633-65-8
Berberinium chloride
Benzodioxide
Berberinum
Berberine chloride [JAN]
NSC-163088
UNII-UOT4O1BYV8
UOT4O1BYV8
EINECS 211-195-9
NSC 163088
NSC-646666
CCRIS 8656
DTXSID8024602
AI3-61834
BERBERINUM [HPUS]
NSC 646666
Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride
DTXCID404602
GNF-PF-4545
BERBERINE CHLORIDE [USP-RS]
Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
BERBERINE HYDROCHLORIDE [WHO-DD]
16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene;chloride
BERBERINE CHLORIDE (USP-RS)
UNII-266464AEJZ
5,6-DIHYDRO-9,10-DIMETHOXYBENZO(G)-1,3-BENZODIOXOLO(5,6-A)QUINOLIZINIUM CHLORIDE
5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride
Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
Berberine hydrochloride bihydrate
DTXSID5030820
BERBERINE CHLORIDE DIHYDRATE [MI]
Berberinum Chloride
16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo(11.8.0.02,10.04,8.015,20)henicosa-1(13),2,4(8),9,14,16,18,20-octaene;chloride
Berbinium, 7,8,13,13a-tetradehydro-9.10-dimethoxy-2,3-(methylene dioxy)-, chloride
Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride, dihydrate
BENZO(G)-1,3-BENZODIOXOLO(5,6-A)QUINOLIZINIUM, 5,6-DIHYDRO-9,10-DIMETHOXY-, CHLORIDE, HYDRATE (1:1:2)
DTXCID3010820
iltrwwgsizfeiw-uhfffaoysa-n
Berberine (chloride)
Berberine HCl
Natural Yellow 18
Berberine chloride form
9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
MFCD00011939
MLS002702530
Natural Yellow 18 (chloride)
CHEBI:31271
NSC163088
633-65-8 (CHLORIDE)
CHEMBL12089
16,17-dimethoxy-5,7-dioxa-13$l^{5}-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(13),2,4(8),9,14,16,18,20-octaen-13-ylium chloride
SMR001233240
NSC646666
SR-01000711827
NCGC00016526-02
NCGC00016526-07
CAS-633-65-8
Prestwick_91
Umbellatine chloride
dimethoxy[?] chloride
Berberine chloride (TN)
MLS002153890
SCHEMBL153906
SPECTRUM1500811
Berberine (chloride) (Standard)
HMS500N07
MSK40203A
CHEBI: 16118
GLXC-04320
HMS1569F14
HMS1921I18
HMS2096F14
HMS2210A06
HMS2235H16
HMS3336C05
HMS3373L14
HMS3655F20
Pharmakon1600-01500811
Tox21_110474
Tox21_200348
1ST40203A
AC-118
CCG-39622
HY-18258R
NSC757795
s2271
AKOS007930622
Tox21_110474_1
CS-3214
FB64955
KS-5294
NSC-757795
5,6-Dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium chloride hydrate
NCGC00091896-01
NCGC00094858-01
NCGC00094858-02
NCGC00257902-01
HY-18258
SY076593
CAS: 638-65-8
B0450
SW196403-2
EN300-116212
Berberine chloride hydrate, technical, >=90% (AT)
SR-01000711827-4
SR-01000711827-6
Z1494829513
Berberine chloride, primary pharmaceutical reference standard
Berberine chloride, British Pharmacopoeia (BP) Reference Standard
Berberine chloride, European Pharmacopoeia (EP) Reference Standard
Benzo[g]-1,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
Berberine chloride, United States Pharmacopeia (USP) Reference Standard
Berberine Chloride, Pharmaceutical Secondary Standard; Certified Reference Material
Berbinium,8,13,13a-tetradehydro-9.10-dimethoxy-2,3-(methylene dioxy)-, chloride
16,17-dimethoxy-5,7-dioxa-13lambda5-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride
5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride;Berberine hydrochloride;7,8,13,13a-Tetradehydro-9,1 0-dimethoxy-2,3-(methylenedioxy)berbinium chloride
9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride
Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)