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Estriol

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Identification
Molecular formula
C18H24O3
CAS number
50-27-1
IUPAC name
(16R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-2,3,16,17-tetrol
State
State

Estriol is typically found in a solid state at room temperature. It exists as crystalline powder that is stable under normal conditions. It should be stored in a cool, dry place away from light to maintain its stability.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.15
Boiling point (Celsius)
540.00
Boiling point (Kelvin)
813.15
General information
Molecular weight
288.38g/mol
Molar mass
288.3810g/mol
Density
1.2300g/cm3
Appearence

Estriol is generally a white to off-white crystalline powder. It does not have a distinct or characteristic odour. Its appearance can vary slightly based on the form and purity of the sample.

Comment on solubility

Solubility of (16R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-2,3,16,17-tetrol

The solubility of the compound (16R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-2,3,16,17-tetrol can be quite complex. This intricately structured molecule exhibits unique characteristics that can affect its interaction with various solvents. Here are some key points to consider regarding its solubility:

  • Polarity: The presence of multiple hydroxyl (-OH) groups suggests a degree of polarity, which can enhance solubility in polar solvents such as water.
  • Hydrophobic Regions: However, the extensive hydrophobic carbon backbone may limit its solubility in such polar environments and favor non-polar solvents, indicating a dual character.
  • Hydrogen Bonding: The hydroxyl groups are capable of forming hydrogen bonds, potentially increasing solubility in alcohols and other hydrogen-bonding solvents.
  • Concentration Dependence: As solubility can be concentration-dependent, careful assessment is necessary to determine the limits of solubility in a given solvent.

In conclusion, while the compound's nature suggests potential solubility in polar solvents due to its functional groups, the intricate balance between its hydrophobic and hydrophilic characteristics makes it an interesting subject for further solubility studies. As with many complex organic compounds, experimentation is key to fully understanding its solubility behavior.

Interesting facts

Interesting Facts about (16R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-2,3,16,17-tetrol

(16R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-2,3,16,17-tetrol is a fascinating compound with significant implications in various fields, particularly in biochemistry and medicinal chemistry. Here are some engaging facts about this remarkable molecule:

  • Complex Structure: The molecular architecture of this compound is intricate, comprising multiple fused rings. This complexity can influence its biological activity and interactions with other molecules.
  • Natural Occurrence: Similar structures can be found in natural products, which often serve as a basis for the development of pharmaceuticals. Studying such compounds helps scientists understand the frequency and nature of biological activity present in nature.
  • Potential Applications: Given its unique structure, this compound may exhibit properties that could be harnessed in drug development, especially in the domains of cancer treatment and hormone regulation.
  • Chirality: The presence of the (16R) stereocenter indicates that this compound can exist in multiple forms (enantiomers), which is critical in pharmacology since different forms can have vastly different effects in biological systems.
  • Research Significance: Ongoing studies are focused on understanding the role of molecules like this one in human health, making it an exciting area for future discoveries.

This compound, with its significant scientific implications and potential applications, exemplifies the rich tapestry of chemistry and biochemistry, demonstrating how even the most complex molecules can lead to groundbreaking advancements in science.