Estradiol Methyl Ether | Solubility of Things

Identification

Molecular formula

C₁₉H₂₆O₃

CAS number

362-29-4

IUPAC name

(16R,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol

State

At room temperature, Estradiol Methyl Ether typically exists as a solid in the form of a white crystalline powder.

Melting point (Celsius)

244.00

Melting point (Kelvin)

517.15

Boiling point (Celsius)

408.50

Boiling point (Kelvin)

681.65

General information

Molecular weight

298.41g/mol

Molar mass

300.4240g/mol

Density

1.1850g/cm³

Appearence

Estradiol Methyl Ether appears as a white crystalline powder. It is often used in laboratory settings and is sensitive to air and light.

Comment on solubility

Solubility of (16R,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol

The solubility of (16R,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol can be quite a complex topic due to its unique structural features. This compound exhibits certain solubility characteristics that are important to understand:

Polarity: The presence of hydroxyl (–OH) groups implies that the compound is likely to have some polar characteristics, which often leads to higher solubility in polar solvents like water.
Hydrophobic Regions: The structure includes multiple carbon rings which are generally hydrophobic; thus, it may also exhibit notable solubility in non-polar solvents such as hexane or chloroform.
Temperature Effects: As is the case with many organic compounds, solubility can significantly change with temperature. Higher temperatures often lead to increased solubility.
Functional Group Influence: The methoxy group may further enhance the solubility in organic solvents by serving as an electron-donating group.

In summary, the solubility behavior of this compound showcases a balance between polar and non-polar characteristics, influenced by the functional groups present. It's essential to consider these factors when predicting solubility in various solvents.

Interesting facts

Interesting Facts About (16R,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol

This compound, known for its complex structure, is a fascinating example of the intricate world of organic chemistry. Here are some intriguing aspects:

Steric Configuration: The notation (16R,17S) indicates specific stereochemistry, which plays a crucial role in biological activity and interactions. This configuration can significantly influence how the compound behaves in biological systems.
Natural Occurrence: Compounds similar to this structure are sometimes found in natural sources, particularly in some plants and fungi. They may exhibit interesting pharmacological properties, leading to ongoing research in pharmacognosy.
Metabolic Pathways: Understanding how this compound is metabolized in the body can provide insights into its potential effects. Metabolic pathways often influence the efficacy and toxicity of chemical compounds in pharmaceutical applications.
Potential Applications: Due to the unique functional groups within its structure, this compound may find applications in medicinal chemistry, particularly in the development of new drugs or therapeutic agents.
Bioactivity: As with many compounds with complex polycyclic structures, there may be exciting links to bioactive properties, such as anti-inflammatory or anticancer effects that warrant further study.
Chemical Synthesis: The synthesis of such multi-functional compounds often involves advanced techniques in organic synthesis. Studying the reactions and pathways to create this compound can enhance our understanding of organic reactivity and mechanism.

The exploration of (16R,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol not only highlights the complex beauty of organic molecules but also opens doors to many scientific inquiries into health, nature, and materials science.