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Corticosterone

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Identification
Molecular formula
C21H30O4
CAS number
50-22-6
IUPAC name
17-(1,5-dihydroxy-1,5-dimethyl-2-oxo-hex-3-enyl)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthrene-3,11-dione
State
State

At room temperature, corticosterone is solid.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.20
Boiling point (Celsius)
518.60
Boiling point (Kelvin)
791.80
General information
Molecular weight
346.46g/mol
Molar mass
346.4600g/mol
Density
1.1400g/cm3
Appearence

Corticosterone is typically a white or slightly yellow crystalline powder.

Comment on solubility

Solubility of 17-(1,5-dihydroxy-1,5-dimethyl-2-oxo-hex-3-enyl)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthrene-3,11-dione (C21H30O4)

The solubility of the compound with the complex name of 17-(1,5-dihydroxy-1,5-dimethyl-2-oxo-hex-3-enyl)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthrene-3,11-dione and the formula C21H30O4 can be quite intriguing due to its structure. This compound exhibits certain characteristics that can influence its solubility in various solvents.

Key Factors Affecting Solubility:

  • Hydroxyl Groups: The presence of multiple hydroxyl (–OH) groups often enhances solubility in polar solvents, such as water. Each hydroxyl group can form hydrogen bonds, increasing interactions with solvent molecules.
  • Hydrophobic Regions: Conversely, the compound also contains hydrophobic (water-repelling) components due to its hydrocarbon structure. This could potentially limit its solubility in polar solvents.
  • Solvent Type: The solubility may vary significantly depending on the solvent used. It is likely to dissolve well in organic solvents like ethanol or methanol compared to straight-chain alkanes due to the dual nature of its functional groups.

In conclusion, while the numerous hydroxyl groups may suggest a higher solubility in water, the large hydrophobic sections present could lead to more complex solubility characteristics. It is essential to consider both the polar and non-polar elements of the compound when predicting solubility outcomes. As with many complex compounds, experimentation can provide the most accurate insight into its solubility behavior.

Interesting facts

Interesting Facts About 17-(1,5-Dihydroxy-1,5-dimethyl-2-oxo-hex-3-enyl)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthrene-3,11-dione

This compound is a fascinating example of the complexity found in organic chemistry, particularly in the realm of natural product synthesis and medicinal chemistry. Here are some intriguing aspects to consider:

  • Structural Complexity: The compound exhibits a multi-ring structure typical of steroids and terpenoids, making it a representative of a large class of bioactive molecules that are prevalent in nature.
  • Hydroxyl Groups: The presence of multiple hydroxyl groups (-OH) suggests potential hydrogen bonding, which can significantly affect its solubility and reactivity. This can enhance the compound's ability to interact with biological targets.
  • Biological Relevance: Compounds like this one often have intriguing biological activities, including anti-inflammatory and antioxidant properties, making them subjects of interest in pharmacological research.
  • Natural Occurrence: The intricate structure may be found in various natural sources, and studying these compounds can provide insight into their ecological roles and potential medicinal uses.

As students and researchers explore this compound, they may be inspired by its intricate design and the potential to innovate through its derivatives or analogs. As Marie Curie famously said, “Nothing in life is to be feared, it is only to be understood.” Understanding the chemistry behind such complex molecules opens the door to new discoveries and advancements in science!

In conclusion, the study of this compound encapsulates the beauty and complexity of organic chemistry, inviting both seasoned scientists and eager students to dive deeper into the world of molecular interactions.

Synonyms
NSC521777
Neuro_000053
Neuro_000223
NCI60_000266
NCI60_004269
DB-082056
17-(1,5-dihydroxy-1,5-dimethyl-2-oxo-3-hexenyl)-2,16-dihydroxy-4,4,9,14-tetramethylestra-1,5-diene-3,11-dione