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Cholesterol

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Identification
Molecular formula
C27H46O
CAS number
57-88-5
IUPAC name
17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
State
State

Cholesterol is in a solid crystalline state at room temperature. It is relatively soluble in organic solvents such as alcohol and acetone but insoluble in water.

Melting point (Celsius)
148.50
Melting point (Kelvin)
421.65
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
386.65g/mol
Molar mass
386.6540g/mol
Density
1.0520g/cm3
Appearence

Cholesterol appears as a white, crystalline substance. It has a slight, yet recognizable odor and is tasteless. Often it comes in powder form but may also be found in its crystalline state depending on how long it has been stored and its environmental conditions.

Comment on solubility

Solubility of 17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

The compound with the chemical formula C27H46O presents intriguing characteristics regarding its solubility. Here are several key points to consider:

  • Hydrophobic Nature: Due to its large hydrocarbon chain and multiple methyl groups, this compound is likely to exhibit significant hydrophobic characteristics.
  • Solvent Compatibility: It is expected to have enhanced solubility in non-polar solvents such as hexane, benzene, and toluene, while its solubility in water is likely to be very low.
  • Alcohol Solubility: The presence of the hydroxyl (-OH) functional group may provide some degree of solubility in alcohols like ethanol or methanol, although the pronounced hydrophobic sections will still limit overall solubility.
  • Temperature Influence: The solubility may increase with higher temperatures, particularly in organic solvents, due to enhanced molecular movement and decreased viscosity.

In summary, one can anticipate that the solubility of this compound will be highly dependent on the solvent type, with a clear preference for non-polar environments while facing challenges in polar solvents such as water. Understanding these nuances in solubility can aid in its applications and handling in laboratory settings.

Interesting facts

Interesting Facts about 17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

This intriguing compound belongs to a class of substances known for their complex structures and significant biological activities. Here are some captivating insights:

  • Structural Complexity: The compound features a multi-ring system typical of steroid-like structures, emphasizing the diverse nature of organic compounds.
  • Natural Occurrence: It is often found in various plant species and has been studied for potential health benefits, which can make it an interesting target for pharmacological research.
  • Biological Activities: Compounds in this category may exhibit properties such as anti-inflammatory, anti-tumor, or antioxidant activities. This broadens its potential applications in medicine and health.
  • Research Potential: Due to its unique structure, it is a subject of interest for chemists studying structure-activity relationships, opening avenues for the development of new therapeutic agents.
  • Synthetic Versatility: The synthesis of this compound can lead to the exploration of various derivatives, further enhancing its utility in both academic and industrial research.

In the domain of medicinal chemistry, understanding compounds like this one can lead to breakthroughs in designing new drugs. As renowned chemist Robert H. Grubbs once said, “The chemistry of life is not a simple matter of recipe, but a complex and deep interplay of parts.” This compound is a perfect example of this intricate interplay.

In summary, the exploration of 17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol reflects the exciting challenges and opportunities present in the field of chemistry.

Synonyms
CHOLESTEROL-3-13C
Cholest-5-en-3-ol
Cholesterol-25,26,27-13C3
335080-97-2
334974-05-9
10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
2,15-dimethyl-14-(6-methylheptan-2-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol
2226426-17-9
10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
765935-41-9
9a,11a-dimethyl-1-(6-methylheptan-2-yl)-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ol
17-(1,5-Dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
Cholest-5-en-3-ol #
Cholest-5-en-3-ol (3 alpha)
DTXSID40859019
10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-ol
17-(1,5-Dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta(a)phenanthren-3-ol
Cholesterol, Plant-Origin
SCHEMBL413494
CHEMBL3184306
DTXCID401474573
BCA46757
BCP32124
GNB02928
ZDA96470
BBL008117
STK069237
AKOS000490908
AKOS016352314
NCGC00142356-01
14-(1,5-dimethylhexyl)-2,15-dimethyltetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec- 7-en-5-ol
DA-48521
SY012864
VS-01833
EN300-718272
F1443-0922
17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol