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Cortexolone 17α-propionate

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Identification
Molecular formula
C22H28O4
CAS number
19608-29-8
IUPAC name
17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
State
State
At room temperature, it is typically a solid.
Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
408.15
Boiling point (Kelvin)
681.30
General information
Molecular weight
416.56g/mol
Molar mass
416.5640g/mol
Density
1.4300g/cm3
Appearence
Cortexolone 17α-propionate appears as a white to off-white crystalline powder.
Comment on solubility

Solubility of 17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione (C22H28O4)

Understanding the solubility of the compound 17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione is crucial for its application in various fields, including pharmaceuticals and materials science. The solubility characteristics can significantly influence its bioavailability and interaction with other materials.

Key Solubility Factors:

  • Molecular Structure: The presence of hydroxyl groups typically enhances solubility in polar solvents.
  • Molecular Weight: With a molecular weight of approximately 356 g/mol, larger molecules often exhibit lower solubility compared to smaller counterparts.
  • Solvent Compatibility: Conducting solubility tests in various solvents can reveal the ideal conditions for dissolving this compound.
  • Temperature Influence: Temperature changes can significantly affect the solubility, as increased temperatures generally lead to higher solubility.

It is important to assess both polar and non-polar solvents to determine the most effective dissolution method. While this compound may have moderate solubility in organic solvents, its solubility in water is likely to be limited due to its hydrophobic regions.

In conclusion, the solubility of 17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione may be variable and heavily influenced by environmental factors. Further studies are necessary to elucidate its solubility profile fully.

Interesting facts

Interesting Facts About 17-(2-Hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione

This intriguing compound belongs to the family of steroids and is characterized by its complex polycyclic structure. Here are some engaging insights into this particular molecule:

  • Biological Significance: Compounds of this type often exhibit biological activity, making them interesting subjects of research, particularly in fields such as pharmacology and biochemistry.
  • Synthetic Applications: It could serve as a synthetic precursor in the production of other important derivatives because of the presence of functional groups that can undergo further reactions.
  • Mechanism of Action: Understanding the mechanism through which similar compounds exert their biological effects can open new avenues in drug design.
  • Structure-Activity Relationship (SAR): The intricate connections within the carbon framework contribute to its potential interactions with biological targets, emphasizing the importance of SAR studies.
  • Chemical Stability: Investigating the stability under various conditions provides insight into the compound's applicability in real-world scenarios.

As quoted by renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This resonates well with studying complex compounds, as exploring various structures and reactions can lead to innovative solutions in medicinal chemistry and beyond.

This compound, with its unique and multifunctional groups, serves as a testament to the thrilling complexity found in organic chemistry. Its exploration could lead to discovering new biochemical pathways or therapeutic agents, highlighting the continued significance of chemical research in modern science.

Synonyms
Dehydrocortocicosterone
SCHEMBL13026136
NSC9702
PD133480
Pregn-4-ene-3,20-trione, 21-hydroxy-