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Norethisterone acetate

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Identification
Molecular formula
C22H28O3
CAS number
51-98-9
IUPAC name
(17-but-2-ynyl-17-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl) acetate
State
State

At room temperature, norethisterone acetate is typically in a solid state.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
429.50
Boiling point (Kelvin)
702.70
General information
Molecular weight
340.47g/mol
Molar mass
340.4710g/mol
Density
1.0790g/cm3
Appearence

Norethisterone acetate appears as a white to off-white crystalline powder. It is odorless and can absorb moisture from the air.

Comment on solubility

Solubility of (17-but-2-ynyl-17-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl) acetate

The solubility of (17-but-2-ynyl-17-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl) acetate is a topic of interest due to its potential applications in various fields, including medicinal chemistry. Here are some key points regarding its solubility:

  • Polarity: The presence of both hydrophobic hydrocarbon chains and a hydroxyl group suggests that this compound may exhibit variable solubility characteristics.
  • Solvent Interaction: It is likely to be more soluble in non-polar organic solvents, such as hexane or chloroform, than in polar solvents like water, due to its structure.
  • Hydroxyl Influence: The hydroxyl group (–OH) can provide some degree of polarity, which may improve its solubility in mixed solvents or alcohols.
  • Temperature Sensitivity: Solubility may increase with temperature, making it important to consider temperature effects in experimental conditions.

In conclusion, while the solubility profile of (17-but-2-ynyl-17-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl) acetate in various solvents can provide rich insights, further experimental data is crucial for definitive assessments. Understanding its solubility will enhance its applicability in chemical formulations and therapeutic contexts.

Interesting facts

Interesting Facts about 17-But-2-ynyl-17-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl Acetate

This complex organic compound belongs to a category often associated with steroidal structures and has intrigued scientists due to its intricate configuration and potential biological activity. Here are several interesting aspects:

  • Structural Diversity: The unique amalgamation of cyclopenta[a]phenanthrene with various side chains contributes to its remarkable structural diversity. Such diversity can lead to varied pharmacological effects, prompting extensive studies in medicinal chemistry.
  • Biological Relevance: Compounds like this one often demonstrate biological significance, particularly in areas such as immunology and cancer research. Understanding the mechanisms by which these compounds interact with biological systems can unveil new therapeutic pathways.
  • Synthetic Challenges: The synthesis of compounds with multiple stereocenters like this one can be particularly challenging, requiring innovative methodologies and techniques. Advances in synthetic organic chemistry often hinge on the ability to create such complex structures efficiently.
  • Potential Applications: Given its steroid-like features, this compound might hold potential as a hormone analog or a precursor in the synthesis of more complex natural products. Research exploring such applications is ongoing and can lead to groundbreaking discoveries.
  • Pharmacodynamics Studies: In pharmacological studies, understanding how such compounds interact with receptors, enzymes, and other biological targets is crucial. These interactions can elucidate mechanisms of action and inform drug design.

In summary, the 17-but-2-ynyl-17-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl acetate is not merely a chemical entity but a gateway to numerous scientific explorations. As scientists delve deeper into its properties and potential applications, we may uncover innovative solutions to some of today's most pressing health concerns.

Synonyms
(17-but-2-ynyl-17-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl) acetate
4146-87-6
DTXSID80274661