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Methandrostenolone

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Identification
Molecular formula
C20H28O2
CAS number
72-63-9
IUPAC name
17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
State
State

At room temperature, Methandrostenolone is generally in a solid state, typically encountered as a crystalline powder.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
489.30
Boiling point (Kelvin)
762.45
General information
Molecular weight
300.44g/mol
Molar mass
300.4410g/mol
Density
1.2000g/cm3
Appearence

Methandrostenolone typically appears as a white crystalline powder.

Comment on solubility

Solubility Characteristics

The compound 17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol presents unique solubility traits largely influenced by its intricate structure and functional groups. Understanding its solubility is crucial for applications in pharmaceuticals and other chemical processes.

Key Aspects of Solubility

  • Polarity: The presence of the dimethylamino group suggests a certain degree of polarity, which may enhance solubility in polar solvents such as water, especially in acidic or basic conditions where protonation or deprotonation may occur.
  • Hydrophobic Regions: With a significant hydrophobic component due to its dodecahydro structure, the compound might exhibit limited solubility in aqueous solutions, favoring organic solvents like ethanol or dimethyl sulfoxide (DMSO).
  • Concentration Impact: Solubility can change with concentration; at higher concentrations, solubility limit may be reached, forming solute clusters or aggregates.
  • Temperature Dependence: As with many organic compounds, solubility is often temperature-dependent; increasing the temperature may enhance solubility in certain solvents.

In summary, while predicting the precise solubility of this compound is complex due to its multifaceted structure, the structural features provide insights into its interactions with various solvents. As with many chemical substances, a thorough investigation through experimentation is vital for determining its solubility profile accurately.

Interesting facts

Interesting Facts about 17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

This unique compound belongs to a class of chemical substances known for their importance in medicinal chemistry. It is particularly interesting due to the following attributes:

  • Structure and Complexity: The compound features a multi-ring structure that incorporates both saturated and unsaturated carbon atoms, contributing to its unique properties. Its extensive system of rings plays a vital role in determining its biological activity.
  • Biological Significance: Compounds with similar structures are often studied for their pharmaceutical potential, especially in fields like oncology and neurology. They could potentially interact with cellular receptors, influencing various biochemical pathways.
  • Functional Groups: The presence of dimethylamino groups suggests potential for enhanced solubility and bioavailability, which are crucial for effectiveness in drug design.
  • Research Applications: Scientists are exploring the therapeutic applications of such compounds, particularly their effects on neurotransmitter systems and endocrine functions.
  • Synthetic Challenges: The synthesis of this compound highlights the complexities of organic chemistry. Researchers face challenges in consistently producing such intricate molecules, which requires advanced techniques in organic synthesis and purification.

In summary, 17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol serves as a reminder of the rich tapestry of organic chemistry. As scientists continue to unravel the mysteries of compounds like this, we are reminded that the interplay between structure and function will always hold the key to understanding their potential in medicine.

Synonyms
17-{[3-(dimethylamino)propyl](methyl)amino}androst-5-en-3-ol
CHEMBL172214
SCHEMBL11273267
DTXSID50861865
(3Beta,17beta)-17-[[3-(dimethylamino)propyl]methylamino]-Androst-5-en-3-ol
NS00121359