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Triamcinolone acetonide

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Identification
Molecular formula
C24H31FO6
CAS number
124-94-7
IUPAC name
17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one
State
State

At room temperature, Triamcinolone acetonide is typically a solid crystalline powder.

Melting point (Celsius)
260.00
Melting point (Kelvin)
533.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
434.50g/mol
Molar mass
434.5020g/mol
Density
1.4500g/cm3
Appearence

Triamcinolone acetonide appears as a white to creamy white, crystalline powder. It is odorless and stable in light.

Comment on solubility

Solubility of 17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one

The solubility of this compound, which features a complex structure and multiple functional groups, can vary greatly depending on several factors including temperature, pH, and the solvent used. In general, understanding the solubility properties is crucial for its application in various fields such as pharmaceuticals and chemical synthesis.

Factors Influencing Solubility

  • Polarity: The presence of hydroxyl and acetyl groups suggests a potential for some level of solubility in polar solvents like water, but the overall hydrophobic nature of the cyclopenta[a]phenanthrene ring may limit its solubility.
  • Temperature: Increasing the temperature typically enhances solubility due to higher kinetic energy, allowing more extensive interactions between solute and solvent.
  • pH Levels: The ionization state of the molecule can shift depending on the pH, potentially improving solubility in acidic or basic environments.
  • Solvent Type: The choice of solvent (e.g., organic solvents like ethanol or non-polar solvents) can have a significant impact on its solubility characteristics.

In summary, while the solubility of 17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one may appear complex, awareness of its solvent interactions and the role of functional groups aids in predicting its behavior in solution. This knowledge is essential for effective application and research involving this compound.

Interesting facts

Interesting Facts about 17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one

This compound, often referred to in scientific contexts for its novel properties, belongs to a class of molecules that are structurally interesting due to their complex arrangements and functional groups. Below are some key points that highlight the significance of this compound:

  • Complex Structure: The intricate cyclopenta[a]phenanthrene framework provides a remarkable example of polycyclic compounds, showcasing how nature's building blocks can combine to form complex entities.
  • Pharmacological Relevance: Compounds similar to this have been investigated for their potential biological activities, particularly in the fields of medicine and pharmacology. Researchers are actively studying their effects on various cell lines.
  • Modification Potential: The presence of functional groups such as acetyl and hydroxy makes this compound an excellent candidate for further chemical modifications, allowing scientists to explore derivatives that may enhance therapeutic effects.
  • Fluorine Substitution: The incorporation of fluorine in organic compounds can dramatically alter their reactivity and biological activity, making this aspect of the compound particularly interesting for drug design.
  • Research Applications: This compound serves as an essential framework in synthetic organic chemistry, serving as a target for synthesis and as a precursor in the development of novel materials and bioactive molecules.

In the words of a chemist, “The beauty of molecular complexity ignites the spark of discovery, leading us to uncharted territories of science.” This compound exemplifies that very spirit as researchers delve into its properties and potential applications.

As science evolves, the full elucidation of the applications and mechanisms behind such complex compounds continues to intrigue both students and seasoned researchers alike.