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Naltrexone

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Identification
Molecular formula
C20H23NO4
CAS number
16676-29-2
IUPAC name
17-allyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
State
State

At room temperature, naltrexone is in a solid state. This compound is stable under ordinary conditions and is typically stored in environments that are free from excessive moisture and light to maintain its efficacy as a pharmaceutical substance.

Melting point (Celsius)
169.50
Melting point (Kelvin)
442.65
Boiling point (Celsius)
465.60
Boiling point (Kelvin)
738.75
General information
Molecular weight
341.41g/mol
Molar mass
341.4130g/mol
Density
1.4290g/cm3
Appearence

Naltrexone appears as a white to slightly off-white powder. It is odorless and crystalline in nature, making it easily identifiable in its pure form. This compound is often used in pharmaceutical applications, and its appearance can be consistent with other similar compounds used for medical purposes.

Comment on solubility

Solubility Overview of 17-allyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol

The solubility characteristics of 17-allyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol (C20H23NO4) are quite intriguing due to its complex structure. Here are some key points regarding its solubility:

  • Polar vs. Nonpolar: The presence of functional groups such as hydroxyl (–OH) contributes polarity, while the hydrocarbon backbone can impart nonpolar characteristics. This duality influences solubility in various solvents.
  • Solvents: It tends to be more soluble in organic solvents like ethanol and chloroform due to its hydrophobic regions, but stability in water is lower due to relatively less polar characteristics.
  • Temperature Dependency: The solubility may increase with temperature, a common trait for many organic compounds, which could enhance the kinetic energy and facilitate dissolution.
  • Complex Interactions: Interaction with solvents can significantly change, with stronger polar solvents potentially leading to hydrogen bonding, which affects overall solubility.

In summary, while the solubility of 17-allyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol is not straightforward, its unique chemical structure undoubtedly influences its compatibility with various solvents, reflecting a fascinating aspect of chemical behavior. Understanding these solubility dynamics is essential for applications in synthesis and formulation.

Interesting facts

Interesting Facts about 17-allyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol

17-allyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol is a fascinating organic compound that belongs to the family of tetracyclic alkaloids. Here are some intriguing aspects of this compound:

  • Structural Complexity: This compound features a complex tetracyclic structure, which is not only visually striking but also plays a significant role in its chemical reactivity and biological activity.
  • Bioactivity Potential: Some derivatives of tetracyclic compounds have been studied for their potential therapeutic effects in medicine, particularly in areas such as oncology and neuropharmacology.
  • Natural Occurrence: Alkaloids similar to this compound can be found in various plant species, indicating that they may possess important ecological functions or adaptive advantages.
  • Synthetic Pathways: The synthesis of such complex structures often requires innovative chemistry techniques, highlighting the ingenuity of synthetic organic chemists.
  • Research Interest: Due to its unique structural features, this compound is of interest in the development of novel pharmaceuticals, making it a subject of ongoing research in organic and medicinal chemistry.

As the field of organic chemistry advances, the study and application of compounds like 17-allyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol continue to expand, potentially leading to breakthroughs in drug discovery and material science. In the words of a renowned chemist, "Chemistry is the science of transformation." This compound is a prime example of how intricate chemical structures can lead to transformative applications in various domains.

Synonyms
Morphinan-3-ol, 17-(2-propenyl)-
Dextrallorphan
Lorfan (Salt/Mix)
Levallorphan tartrate (Salt/Mix)
SCHEMBL209271
CHEMBL608539
BDBM92849
DTXSID80859295
NSC_9036
17-(prop-2-en-1-yl)morphinan-3-ol
CAS_152-02-3
L001162
Q5268487
17-prop-2-enyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol