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Clozapine

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Identification
Molecular formula
C18H19ClN4
CAS number
5786-21-0
IUPAC name
17-azapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2,4,6,8,10,12(20),13,15,17-decaene
State
State

At room temperature, clozapine is in the form of a solid, specifically a crystalline powder. It does not have a volatile state under standard conditions, which makes handling easier in controlled environments.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
524.00
Boiling point (Kelvin)
797.15
General information
Molecular weight
326.83g/mol
Molar mass
326.8310g/mol
Density
1.2800g/cm3
Appearence

Clozapine appears as a yellow crystalline powder. It is known for its characteristic color and crystal form, making it identifiable in its pure form.

Comment on solubility

Solubility of 17-azapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2,4,6,8,10,12(20),13,15,17-decaene

The solubility of the compound 17-azapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2,4,6,8,10,12(20),13,15,17-decaene can be described as complex and varies significantly depending on the solvent and conditions applied. Here are some key points regarding its solubility:

  • Organic Solvents: This compound likely shows better solubility in organic solvents due to its hydrophobic characteristics, typical of polycyclic compounds.
  • Aqueous Solubility: The solubility in water is expected to be limited because of its extensive hydrophobic structure, likely resulting in a low partition coefficient.
  • Temperature Influence: An increase in temperature can enhance solubility in some solvents, aiding dissolution.
  • pH Dependency: If the compound possesses any ionizable groups, the solubility may be influenced by the pH of the solvent.

Understanding the solubility behavior of this compound is crucial for applications in pharmaceuticals, material science, and organic synthesis. "Every solvent has its own personality," and recognizing these interactions provides insight into the compound's usability in various chemical contexts.

Interesting facts

Interesting Facts about 17-Azapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2,4,6,8,10,12(20),13,15,17-decaene

17-Azapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2,4,6,8,10,12(20),13,15,17-decaene is a fascinating compound in the realm of organic chemistry, with a range of attributes that intrigue both chemists and researchers. Here are some key highlights:

  • Unique Structure: The compound boasts a complex polycyclic framework that is not only intricate but also offers unique properties due to its structural geometry.
  • Aza-Substitution: The presence of nitrogen in its structure (as indicated by the "aza" prefix) contributes to interesting electronic and steric properties, which can influence its reactivity and interaction with other molecules.
  • Potential Applications: Research is ongoing into its potential applications in medicinal chemistry and material science. The unique arrangements within the molecule could lead to novel drug designs or advanced materials.
  • Isomerism: This compound can exhibit geometric isomerism, providing an opportunity for further exploration of its isomers with distinct chemical behaviors and characteristics.
  • Studying Natural Processes: Compounds closely related to this structure are often studied for their roles in natural processes, offering insights into biochemical pathways.

As a quoted observation from a leading chemist, "Understanding the complexities of such unique compounds enables breakthroughs not just in chemistry but across multiple scientific fields." This reflects the pivotal role of examining intricate molecules like 17-azapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2,4,6,8,10,12(20),13,15,17-decaene in advancing our knowledge of molecular interactions and innovations.

Thus, this compound stands at the intersection of structure, function, and potential, making it an essential subject for ongoing study in the field of chemistry.

Synonyms
12-Azabenzo(a)pyrene
Benzo(h)thebenidine
DIBENZO(i,lmn)PHENANTHRIDINE
24496-65-9
8H56FF0MYE
NSC-154310
Dibenzo[i,lmn]phenanthridine
12-AZABENZO[A]PYRENE
CCRIS 1601
NSC 154310
Benzo(h)thebenidine (9CI)
BRN 1575133
NSC154310
UNII-8H56FF0MYE
DTXSID90179254