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Cortisone

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Identification
Molecular formula
C21H28O5
CAS number
53-06-5
IUPAC name
17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
State
State
At room temperature, cortisone is typically in a solid state as a crystalline powder.
Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
525.40
Boiling point (Kelvin)
798.60
General information
Molecular weight
360.45g/mol
Molar mass
360.4450g/mol
Density
1.3000g/cm3
Appearence

Cortisone appears as a white or nearly white crystalline powder. It is odorless.

Comment on solubility

Solubility of 17-Hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one (C21H28O5)

The solubility of 17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one is an intriguing aspect to consider for understanding its chemical behavior and potential applications. Here are some key points regarding its solubility:

  • Polar vs Non-Polar Solvent Interaction: This compound, being a large organic molecule with multiple functional groups, may display varying solubility in polar and non-polar solvents. Generally, compounds with alcohol or ketone groups, like this one, are more soluble in polar solvents.
  • Hydrogen Bonding: The presence of hydroxyl (-OH) groups on the molecule suggests that it can form hydrogen bonds, which typically enhances its solubility in water to some extent.
  • Lipid Solubility: Conversely, the hydrocarbon backbone likely provides significant hydrophobic characteristics, making it more soluble in lipophilic environments, such as organic solvents like hexane or chloroform.

In summary, the solubility of this compound can be characterized as:

  1. Potentially soluble in polar solvents due to its hydroxyl functional group.
  2. More likely to be soluble in non-polar organic solvents because of its extensive hydrophobic structure.

Understanding the solubility characteristics of C21H28O5 is essential for its further applications in biochemical and pharmaceutical fields.

Interesting facts

Interesting Facts About 17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

This compound is a fascinating member of the steroid family, showcasing a complex structure and a variety of biological interactions. It primarily functions as a synthetic steroid hormone, and its significance is evident in several fields of research.

Key Characteristics

  • Biological Activity: The compound exhibits hormonal activity, making it involved in various physiological processes, including growth and development.
  • Synthetic Pathways: Primarily synthesized in laboratories, this compound provides insights into synthetic organic chemistry and the production of complex natural products.
  • Potential Applications: Research on this compound has potential implications in steroid hormone therapy, anti-inflammatory treatments, and even cancer research due to its complex interactions with biological systems.

Moreover, studying this compound can enhance our understanding of steroid biosynthesis and metabolic pathways. As a result, future investigations could explore:

  1. The compound’s interaction with specific receptors in the human body.
  2. How slight modifications of its structure might influence its biological activity.
  3. Potential side effects and therapeutic profiles when used in clinical applications.

In summary, 17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one is not just a complex molecule but a gateway into the world of steroid chemistry and its vast therapeutic horizons. Its exploration is crucial for anyone delving into hormonal research and synthetic steroid development.

Synonyms
17-Hydroxyandrostan-3-one
Etiocholan-17.beta.-ol-3-one
Anaprotin
5.beta.,17.beta.-Hydroxyandrostan-3-one
5.beta.-Androstan-3-one, 17.beta.-hydroxy-
5B-DIHYDROTESTOSTERONE
Androstan-3-one, 17-hydroxy-, (5.alpha.,17.beta.)-
Oprea1_456186
SCHEMBL9340073
NVKAWKQGWWIWPM-UHFFFAOYSA-N
AAA57124
BCP22808
FAA29566
NSC15460
NSC61692
BBL028114
NSC-61692
STK366316
AKOS002232213
AKOS016303784
NCGC00249620-01
17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
VS-08671
AB00987792-01
1-hydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-one
17-HYDROXY-10,13-DIMETHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE
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