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Corticosterone

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Identification
Molecular formula
C21H30O4
CAS number
50-22-6
IUPAC name
17-hydroxy-10,13,17-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
State
State

At room temperature, corticosterone is typically a solid.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
446.83
Boiling point (Kelvin)
719.98
General information
Molecular weight
346.47g/mol
Molar mass
346.4640g/mol
Density
1.2460g/cm3
Appearence

Corticosterone can appear as a white or almost white crystalline powder. It may also form colorless crystals under certain conditions.

Comment on solubility

Solubility of 17-hydroxy-10,13,17-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one

The solubility characteristics of 17-hydroxy-10,13,17-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one are of significant interest, particularly given its complex structure. Generally, the solubility of such steroid-like compounds is influenced by several factors:

  • Non-Polar Characteristics: The molecule exhibits considerable hydrophobic properties due to its extensive hydrocarbon framework, leading to expected low solubility in water.
  • Dimensional Structure: The bulky structure could hinder interactions with polar solvents, further decreasing its solubility in aqueous environments.
  • Solvent Compatibility: It may show improved solubility in organic solvents like ethanol, methanol, or chloroform, where Van der Waals forces can facilitate solvation.

In conclusion, while the compound can be expected to be insoluble or only sparingly soluble in water, it likely possesses enhanced solubility in organic solvents. As stated, "The solubility of organic compounds often hinges on their structural and functional characteristics, as well as the nature of the solvent used."

Interesting facts

Interesting Facts about 17-hydroxy-10,13,17-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one

The compound 17-hydroxy-10,13,17-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one is a fascinating member of the steroid family, primarily recognized for its structural complexity and varied biological activities. It is often referred to in scientific literature due to its significant roles in the field of biochemistry and pharmaceuticals.

Key Features:

  • Synthetic Origins: This compound is synthesized through intricate multi-step chemical reactions, showcasing the elegance of organic synthesis.
  • Biological Relevance: It interacts with various biological pathways, making it a subject of interest in the study of hormonal activities and their implications in health.
  • Research Potential: The compound is under investigation for its potential therapeutic applications, offering insights into new treatments for hormonal imbalances.

Moreover, this compound exemplifies the intricate relationship between structure and function, which is a foundational concept in medicinal chemistry. As stated by renowned chemist Linus Pauling, "The structure of a molecule governs its properties and behavior." This relationship underscores the importance of detailed structural analysis in understanding how compounds behave biologically.

Applications:

  • Potential use in hormone replacement therapy
  • Investigation into anti-inflammatory properties
  • Study as a lead compound for new drug development

In conclusion, the compound 17-hydroxy-10,13,17-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one is a prime example of how complex organic molecules can have profound implications in both scientific research and practical applications in medicine.

Synonyms
1-hydroxy-1,9a,11a-trimethyl-2H,3H,3aH,3bH,4H,5H,8H,9H,11H-cyclopenta[a]phenanthren-7-one