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Norgestrel

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Identification
Molecular formula
C21H28O2
CAS number
6533-00-2
IUPAC name
17-hydroxy-13-methyl-17-[(1R)-1-methylallyl]-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
State
State

Norgestrel is a solid at room temperature.

Melting point (Celsius)
206.00
Melting point (Kelvin)
479.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
312.45g/mol
Molar mass
312.4460g/mol
Density
1.0000g/cm3
Appearence

Norgestrel is typically a white to slightly off-white, crystalline powder. It has little to no odor and is recognizable by its specific crystalline form.

Comment on solubility

Solubility of 17-hydroxy-13-methyl-17-[(1R)-1-methylallyl]-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

The solubility of complex organic compounds, such as 17-hydroxy-13-methyl-17-[(1R)-1-methylallyl]-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one, can be influenced by several factors:

  • Polarity: This compound exhibits a combination of hydrophobic and hydrophilic characteristics, which can lead to variable solubility in polar and non-polar solvents.
  • Temperature: Solubility generally increases with temperature. The extent of this increase may vary based on the solvent used.
  • Solvent Type: Non-polar solvents (such as hexane or toluene) may dissolve this compound more effectively due to its large hydrophobic regions.
  • Functional Groups: The presence of hydroxyl groups can enhance solubility in alcohols or other polar solvents, although the overall bulkiness may counteract this effect.

In summary, while specific quantitative solubility data may not be readily available, the **dynamic nature** of its molecular structure suggests a need to conduct experiments to **determine the precise solubility** in various solvents. As a related note, it's often quoted in chemistry, “Like dissolves like,” which serves as a good guideline for predicting solubility behavior.


Interesting facts

Interesting Facts About 17-hydroxy-13-methyl-17-[(1R)-1-methylallyl]-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

This complex organic compound, belonging to the class of steroids, boasts a fascinating array of characteristics that underline its importance in both biological systems and medicinal chemistry.

Biological Relevance

17-hydroxy-13-methyl-17-[(1R)-1-methylallyl]-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one is structurally related to naturally occurring steroids. Here are some key points about its biological significance:

  • Hormonal Activity: The compound may exhibit hormone-like properties, influencing various physiological processes such as metabolism and reproductive functions.
  • Therapeutic Potential: Due to its structural resemblance to steroid hormones, it is a potential candidate for drug development, especially in the treatment of hormonal imbalances.

Synthetic Pathways

The synthesis of this compound is of great interest in organic chemistry. Notable facts include:

  • Complex Synthesis: The intricate molecular architecture requires advanced synthesis techniques, making it a subject of study for synthetic chemists.
  • Precursor to Other Compounds: It can serve as a precursor in the synthesis of other biologically active molecules, a critical aspect for green chemistry endeavors.

Applications in Research

The study of this compound extends to various areas of research:

  • Natural Products Chemistry: Its relationship to steroids makes it a significant focus in the exploration of natural product compounds.
  • Pharmacology: Researchers are investigating its pharmacokinetic properties to determine its potential therapeutic uses.

In summary, the exploration of 17-hydroxy-13-methyl-17-[(1R)-1-methylallyl]-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one exemplifies the intersection of organic chemistry and biological function, showcasing how intricate molecular designs can lead to profound implications in health and industry.