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Estrone sulfate

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Identification
Molecular formula
C18H23O5S
CAS number
61849-06-7
IUPAC name
(17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl) sulfate
State
State
Solid at room temperature, typically found as a fine white crystalline powder.
Melting point (Celsius)
215.00
Melting point (Kelvin)
488.00
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.00
General information
Molecular weight
350.46g/mol
Molar mass
350.4550g/mol
Density
1.3000g/cm3
Appearence

Estrone sulfate is a white, crystalline powder. It may also appear as fine white crystals or crystalline powder, and it is often odorless.

Comment on solubility

Solubility of (17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl) sulfate

The solubility of (17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl) sulfate, represented by the chemical formula C18H23O5S, can be influenced by several factors:

  • Polarity: The sulfate group (-OSO3) enhances the polarity of the molecule, allowing for potential interactions with polar solvents like water.
  • Hydrogen Bonding: The presence of hydroxy groups can facilitate hydrogen bonding, which typically enhances the solubility in polar solvents.
  • Hydrophobic Interactions: On the other hand, the hydrocarbon portion of the molecule tends to be hydrophobic, which may limit solubility in aqueous solutions.

Overall, the solubility of this compound could be characterized as moderate to low in water, yet it might exhibit better solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO). The balance between its hydrophilic and hydrophobic characteristics plays a critical role in determining the actual solubility behavior.

Thus, it's essential to consider the solvent environment when conducting experiments involving this compound, as solubility can significantly influence reaction dynamics and biological interactions.

Interesting facts

Exploring 17-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl Sulfate

This compound, often referred to in shorthand as an important derivative in the realm of steroid chemistry, holds fascinating implications not just in organic chemistry but also in fields like biochemistry and pharmacology. Here are some intriguing facts about this compound:

  • Steroid Origins: It is derived from steroid backbones, showcasing how subtle modifications in structure can lead to various biological activities.
  • Biological Significance: Compounds like this sulfate ester often play significant roles in hormonal functions and regulatory mechanisms in living organisms.
  • Sulfonate Group Functionality: The sulfate moiety introduces unique chemical properties, enhancing solubility and reactivity which can be exploited in drug design.
  • Therapeutic Potential: Research into similar compounds has revealed potential therapeutic applications, particularly in managing diseases influenced by steroid hormones.
  • Analytical Techniques: This compound can be analyzed using state-of-the-art techniques such as mass spectrometry and NMR spectroscopy, key tools in identifying and characterizing complex organic molecules.

As we delve deeper into the world of this compound, we find a crisscross of chemistry and life science, illustrating that the molecular composition of a substance can dictate its potential uses and significance seamlessly. Indeed, as Albert Einstein eloquently stated, “Everything should be made as simple as possible, but no simpler,” underscoring the elegance of chemical structure-function relationships.

Studying such compounds not only enhances our understanding of complex biochemical pathways but also inspires ongoing research into innovative applications that hold promise for future scientific advancements.