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Hydrocortisone

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Identification
Molecular formula
C21H30O5
CAS number
50-23-7
IUPAC name
17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
State
State

At room temperature, hydrocortisone is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.00
Boiling point (Celsius)
568.00
Boiling point (Kelvin)
841.00
General information
Molecular weight
362.47g/mol
Molar mass
362.4660g/mol
Density
1.3000g/cm3
Appearence

Hydrocortisone typically appears as a white or almost white crystalline powder. It is often odorless and has a slight, characteristic odor. The powder is known for being practically insoluble in water, slightly soluble in ethanol, and freely soluble in acetone.

Comment on solubility

Solubility of 17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione (C21H30O5)

The solubility of complex organic compounds like 17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione can be influenced by various factors. This particular compound, with its intricate structure, exhibits unique solubility characteristics:

  • Polar Functional Groups: The presence of hydroxyl (–OH) and acetyl (–C(=O)CH3) groups typically enhances solubility in polar solvents like water.
  • Hydrophobic Regions: The large hydrocarbon framework may reduce solubility in aqueous environments, favoring non-polar or organic solvents.
  • Temperature Dependence: Solubility can increase with temperature for many organic compounds, although specific behavior should be characterized experimentally.

In summary, while this compound may show some degree of solubility in polar solvents due to its functional groups, its overall solubility profile is likely to be complex and highly dependent on the solvent's characteristics. Research and experimentation are essential to fully understand the solubility behavior of such intricate compounds in various environments.

Interesting facts

Interesting Facts About 17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

This compound, a member of the steroid family, showcases the intricate chemistry of natural and synthetic substances. Its structural complexity is a striking reminder of the diversity found within organic compounds. Here are some engaging insights into its significance:

  • Biological Relevance: Compounds within this category are often studied for their biological activities. They can mimic or inhibit various hormones, which can have broad implications in pharmaceutical research.
  • Source: Many steroids are derived from natural sources, such as plants and animals. Studying these compounds can lead to advancements in medicinal chemistry and drug development.
  • Functional Groups: The presence of multiple functional groups, such as hydroxyl and carbonyl groups, significantly influences the reactivity and biological properties of this compound. Understanding these groups is essential for predicting behavior in biological systems.
  • Synthetic Applications: The complexity of this compound makes it an intriguing target for chemists. Researchers often explore synthetic pathways to create analogs that may enhance or diminish specific biological activities.

As one knowledgeable source puts it, "The study of steroids is not only about their chemistry but also about unlocking their potential for therapeutic use." With ongoing research, compounds like this one continue to be at the forefront of drug development, offering hope for treating various conditions.

Overall, the exploration of 17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione serves as a fascinating example of how intricate molecular structures can lead to significant scientific advancements.

Synonyms
Fernisone
1192475-75-4
1-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-7,10-dione
17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
delta-Cortone
delta-E
Nisone (Salt/Mix)
Cortancyl (Salt/Mix)
Delcortin (Salt/Mix)
Deltalone (Salt/Mix)
MLS002638114
Metrevet (Veterinary) (Salt/Mix)
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
17.alpha.,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
SCHEMBL3408330
CHEMBL1732663
DTXSID10858978
HMS2232G16
HMS3373F11
BBL023863
STL069503
AKOS005111097
SMR001317864
VS-07535
EN300-49849