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Cortisol

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Identification
Molecular formula
C21H30O5
CAS number
50-23-7
IUPAC name
17-hydroxy-2-(hydroxymethylene)-10,13,17-trimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
State
State
At room temperature, cortisol is typically in a solid state.
Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
546.00
Boiling point (Kelvin)
819.15
General information
Molecular weight
362.46g/mol
Molar mass
362.4600g/mol
Density
1.3000g/cm3
Appearence

Cortisol, a steroid hormone, is typically present as a crystalline powder. The appearance can vary slightly depending on the specific formulation and purity, but it generally appears in white to off-white crystals. In its pure form, it is often odorless.

Comment on solubility

Solubility of 17-hydroxy-2-(hydroxymethylene)-10,13,17-trimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one (C21H30O5)

The solubility of the compound C21H30O5 can be characterized by several key factors related to its structure:

  • Polarity: Given the presence of multiple hydroxyl (–OH) groups, this compound exhibits some degree of polarity, which can enhance its solubility in polar solvents.
  • Hydrophobic Regions: The alkane-like portions of the structure provide hydrophobic characteristics, suggesting low solubility in water. This can lead to preferential solubility in organic solvents.
  • Solvent Effects: Generally, this compound may dissolve well in solvents like:
    • Alcohols (e.g., ethanol)
    • Aprotic solvents (e.g., dichloromethane)
    • Organic oils

In conclusion, the solubility of C21H30O5 is influenced by both its polar hydroxyl groups and hydrophobic carbon skeleton, leading to a behavior typical of compounds that are more soluble in organic solvents than in aqueous environments. As with many chemical compounds, understanding the interplay of structure and environment is key to predicting solubility characteristics.

Interesting facts

Interesting Facts About 17-Hydroxy-2-(hydroxymethylene)-10,13,17-trimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

This intriguing compound belongs to a class of steroids and is notable for its complex structure and various biological activities. Here are some remarkable aspects:

  • Structural Complexity: The compound features a unique bicyclic structure, showcasing a combination of multiple rings, which can significantly influence its biological properties.
  • Biological Relevance: Its structure is reminiscent of similar steroid compounds known for their hormonal activity, indicating potential applications in pharmacology and medicine.
  • Potential Therapeutic Uses: Compounds like this one have been studied for their anti-inflammatory and anabolic effects, which are vital in the development of therapeutic agents.
  • Synthesis: The synthesis of such compounds often involves intricate organic chemistry techniques, highlighting the creativity and innovation in the field of chemical research. Scientists strive for efficient methods to create these molecules with high purity.

In the words of a renowned chemist, "The beauty of chemistry lies in its complexity and the myriad ways molecules can interact in our world." Such compounds open the door to a deeper understanding of biochemical pathways and potential medicinal benefits.

Studying compounds like 17-hydroxy-2-(hydroxymethylene)-10,13,17-trimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one not only expands our knowledge of organic chemistry but also broadens our horizons for medical advancements.

Synonyms
(5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2-(hydroxymethylene)-10,13,17-trimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
PD033033
1,7-dihydroxy-1,9a,11a-trimethyl-2H,3H,3aH,3bH,4H,5H,5aH,6H,9H,9bH,10H,11H-cyclopenta[a]phenanthrene-8-carbaldehyde