Skip to main content

1,7-Naphthyridine

ADVERTISEMENT
Identification
Molecular formula
C8H6N2
CAS number
253-61-6
IUPAC name
1,7-naphthyridine
State
State
1,7-Naphthyridine is a solid at room temperature.
Melting point (Celsius)
54.00
Melting point (Kelvin)
327.15
Boiling point (Celsius)
269.00
Boiling point (Kelvin)
542.15
General information
Molecular weight
116.15g/mol
Molar mass
116.1260g/mol
Density
1.2430g/cm3
Appearence

1,7-Naphthyridine typically appears as a crystalline solid. It is colorless or exhibits a pale yellow tint.

Comment on solubility

Solubility of 1,7-Naphthyridine

1,7-Naphthyridine, with the chemical formula C8H6N, exhibits intriguing solubility characteristics that can be summarized as follows:

  • Water Solubility: This compound demonstrates limited solubility in water, which can be attributed to the hydrophobic nature of the naphthyridine ring system.
  • Solvents: 1,7-Naphthyridine is more soluble in organic solvents such as:
    • Dimethyl sulfoxide (DMSO)
    • Acetone
    • Alcohols
  • Temperature Dependency: The solubility tends to increase with rising temperature, making warm solutions more effective for dissolving the compound.

In summary, while 1,7-naphthyridine shows limited aqueous solubility, it finds better solubility in organic solvents, thus enhancing its utility in various chemical applications. As with many organic compounds, understanding the solubility behavior is essential for efficient use in synthesis and analysis.

Interesting facts

Interesting Facts about 1,7-Naphthyridine

1,7-Naphthyridine is a fascinating aromatic compound that has garnered attention in various fields of chemistry, particularly in medicinal and organic chemistry. Below are some insights that highlight its significance:

  • Structural Features: 1,7-Naphthyridine contains a fused bicyclic ring structure, comprising a pyridine ring fused to a naphthalene derivative. This unique arrangement contributes to its intriguing chemical properties and reactivity.
  • Biological Relevance: Numerous studies have indicated that compounds related to 1,7-naphthyridine exhibit a variety of biological activities. Many derivatives show promise as potential antimicrobial, antiviral, and anticancer agents, making them important candidates for pharmaceutical development.
  • Applications in Research: Due to its heterocyclic nature, 1,7-naphthyridine is often used as a key building block in the synthesis of more complex molecules. Researchers frequently utilize it in the development of ligands for metal coordination and in organic synthesis processes.
  • Reactivity: This compound can undergo various chemical reactions, including substitutions and functionalizations. Its reactivity makes it a valuable subject of study for organometallic and coordination chemistry.
  • Potential in Drug Design: The presence of nitrogen atoms in the heterocyclic ring enhances its ability to participate in hydrogen bonding, which is crucial in drug-receptor interactions. As a result, this molecule is often explored in drug design strategies to improve biological efficacy.

In summary, 1,7-naphthyridine stands out not only for its structural elegance but also for its diverse applications in science and medicine. Its ongoing exploration in the lab underscores the ever-evolving relationship between chemistry and biological science.

Synonyms
1,7-NAPHTHYRIDINE
253-69-0
1,7-Diazanaphthalene
1,7-Pyridopyridine
UNII-NA3KH11MLA
NA3KH11MLA
CHEBI:36626
1,7-Naphthyridine(6CI,7CI,8CI,9CI)
DTXSID20179944
[1,7]naphthyridine
MFCD11521576
SCHEMBL89126
DTXCID80102435
AKOS006322862
DB-067384
EN300-93348
Q27116906
Z1198330965
Ethyl 4-hydroxy-2-[(4-methoxybenzyl)sulfanyl]-5-pyrimidinecarboxylate #
838-701-6