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Methylnaltrexone

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Identification
Molecular formula
C14H25NO
CAS number
152054-01-0
IUPAC name
1,7,7-trimethyl-3-(propylaminomethyl)norbornan-2-one
State
State

At room temperature, the compound is typically a solid. However, its state can change under certain conditions of temperature and pressure.

Melting point (Celsius)
39.00
Melting point (Kelvin)
312.15
Boiling point (Celsius)
246.85
Boiling point (Kelvin)
520.00
General information
Molecular weight
199.32g/mol
Molar mass
199.3170g/mol
Density
0.9302g/cm3
Appearence

The compound appears as a off-white or white crystalline solid, commonly presented in its pure form. Impurities or different states of hydration can cause slight variations in color.

Comment on solubility

Solubility of 1,7,7-trimethyl-3-(propylaminomethyl)norbornan-2-one

The solubility of the compound 1,7,7-trimethyl-3-(propylaminomethyl)norbornan-2-one can be characterized by several important factors:

  • Polarity: The presence of the propylaminomethyl group can influence the overall polarity of the compound, potentially enhancing its solubility in polar solvents.
  • Hydrogen Bonding: The ability of this compound to engage in hydrogen bonding due to its amine functionality may also facilitate its solubility, especially in protic solvents.
  • Solvent Compatibility: This compound may exhibit variable solubility in different solvents. For example:
    • In polar solvents (like water or alcohols), the solubility might be moderate to high due to hydrogen bonding.
    • In non-polar solvents (such as hydrocarbons), solubility may decrease significantly, reflecting its non-polar characteristics.

It is important to note that the exact solubility value can vary under different conditions, such as temperature and pH. Therefore, careful experimental measurements are needed to determine the precise solubility of this compound in various solvents effectively.

Interesting facts

Interesting Facts about 1,7,7-trimethyl-3-(propylaminomethyl)norbornan-2-one

1,7,7-trimethyl-3-(propylaminomethyl)norbornan-2-one is a fascinating compound that showcases the intricate connections between structure and function in organic chemistry. As a derivative of norbornane, this compound exemplifies the unique properties associated with bicyclic structures. Here are some interesting aspects:

  • Synthetic Versatility: This compound is often synthesized using various methods that highlight the creativity in organic synthesis, allowing chemists to explore multiple reaction pathways.
  • Biological Relevance: The structure of this compound, especially the presence of amine groups, can impact its bioactivity, making it a candidate for research in medicinal chemistry.
  • Chiral Centers: The presence of multiple chiral centers in this compound means it can exist in several stereoisomeric forms, each potentially exhibiting different biological activities.
  • Hydrophobic Characteristics: Due to its hydrocarbon backbone, the compound may demonstrate significant hydrophobic characteristics, influencing how it interacts with biological membranes.

In the world of medicinal chemistry, derivatives of norbornane have been explored for various therapeutic applications, including:

  1. Potential as analgesics
  2. Behavioral studies regarding their effects on neurochemistry
  3. Exploring the compound's interaction with various receptors

In the words of chemists: "The magic of organic chemistry lies in its ability to create profoundly different biological effects from subtle changes in molecular structure." This statement rings true in the study of compounds like 1,7,7-trimethyl-3-(propylaminomethyl)norbornan-2-one, where even small modifications can open doors to significant discoveries.