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Phentermine

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Identification
Molecular formula
C10H15N
CAS number
122-09-8
IUPAC name
1,7,7-trimethyl-N-[(4-phenylphenyl)methyl]norbornan-2-amine
State
State

At room temperature, Phentermine is commonly found in a solid form. It is typically handled and stored as a powder or contained within pharmaceutical tablets or capsules, making it stable for oral administration.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
368.00
Boiling point (Kelvin)
641.15
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
0.9000g/cm3
Appearence

Phentermine typically appears as a white, crystalline powder. It may also be formulated into tablet or capsule form when used in pharmaceutical preparations. The compound is known for its distinct crystalline structure, which is indicative of its purity and pharmaceutical grade.

Comment on solubility

Solubility of 1,7,7-trimethyl-N-[(4-phenylphenyl)methyl]norbornan-2-amine

The solubility of 1,7,7-trimethyl-N-[(4-phenylphenyl)methyl]norbornan-2-amine can be understood by considering several key factors that influence the behavior of this compound in various solvents:

  • Polarity: The overall polarity of the molecule plays a crucial role. This compound contains both aliphatic and aromatic groups, suggesting a combination of polar and nonpolar characteristics.
  • Functional Groups: The presence of the amine functional group may lead to better solubility in polar solvents due to hydrogen bonding capabilities.
  • Hydrophobic Interactions: The trimethyl and phenyl groups contribute to hydrophobic interactions, potentially rendering the compound less soluble in water but more soluble in organic solvents.

As a result, we can infer:

  1. Higher solubility in: Organic solvents such as ethanol, methanol, and possibly DMSO.
  2. Lower solubility in: Aqueous solutions due to its bulky nonpolar portions.

In conclusion, the solubility of 1,7,7-trimethyl-N-[(4-phenylphenyl)methyl]norbornan-2-amine is expected to be more favorable in organic environments compared to aqueous conditions. However, specific experimental data would be necessary to confirm these hypotheses regarding its solubility behavior.

Interesting facts

Interesting Facts about 1,7,7-Trimethyl-N-[(4-phenylphenyl)methyl]norbornan-2-amine

This intriguing compound belongs to the class of amines and exhibits a fascinating structure that has captured the interest of chemists across various fields. Here are some compelling aspects of this compound:

  • Structural Complexity: The norbornane framework, characterized by its bicyclic structure, contributes to the compound's unique properties. This framework allows for interesting spatial orientation and steric interactions that can influence reactivity.
  • Substituent Effects: The presence of trimethyl groups and a phenyl-phenyl substituent adds both bulk and electronic considerations, making this compound an excellent candidate for studying substituent effects in organic reactions.
  • Applications in Drug Design: Compounds like this one are often investigated for their potential roles in medicinal chemistry. Their ability to mimic neurotransmitters or interact with biological receptors makes them significant in drug discovery.
  • Research Significance: This compound can be pivotal in understanding the principles of chirality and stereochemistry owing to its asymmetric centers, offering an array of possibilities for optical activity studies.
  • Physical Properties: While specific numerical data is not provided, the compound is likely to showcase unique solubility characteristics due to its structural elements, affecting how it interacts in various chemical environments.

In summary, 1,7,7-trimethyl-N-[(4-phenylphenyl)methyl]norbornan-2-amine serves as a prime example of the interplay between structure and function in organic chemistry. Its complexity, potential applications in pharmacology, and unique physicochemical attributes make it a compound worth exploring further.