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Estradiol

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Identification
Molecular formula
C18H24O2
CAS number
50-28-2
IUPAC name
(17S)-10,13,17-trimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-diol
State
State

Solid at room temperature.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
377.61
Boiling point (Kelvin)
650.76
General information
Molecular weight
272.38g/mol
Molar mass
272.3820g/mol
Density
1.1698g/cm3
Appearence

Estradiol is a white crystalline powder. It is crystalline in appearance and lacks any distinct odor.

Comment on solubility

Solubility of (17S)-10,13,17-trimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-diol

The solubility of organic compounds can be quite complex, and the solubility behavior of (17S)-10,13,17-trimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-diol is no exception. This compound, due to its unique structure, may exhibit a range of solubility characteristics depending on several factors:

  • Polarity: Being a polycyclic compound with multiple functional groups, the presence of hydroxyl (-OH) groups can enhance its polarity, potentially increasing solubility in polar solvents like water.
  • Hydrophobic Regions: The extensive hydrocarbon framework contributes to hydrophobicity, which could lead to limited solubility in water but increased solubility in non-polar solvents such as hexane or chloroform.
  • Temperature: Solubility may also be influenced by temperature changes; generally, increasing the temperature can enhance solubility for many organic compounds.
  • pH Levels: Changes in pH can alter the ionization of functional groups, which might further impact the solubility in aqueous solutions.

As a result, it is essential to consider these factors when evaluating the solubility of (17S)-10,13,17-trimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-diol. In experimental contexts, conducting solubility tests in various solvents and conditions will yield the most accurate understanding of its solubility behavior.

Interesting facts

Interesting Facts about (17S)-10,13,17-trimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-diol

This compound, also known for its complex polycyclic structure, belongs to a class of compounds that are essential in various fields of study, including organic chemistry and medicinal chemistry. Here are some captivating aspects to consider:

  • Steroidal Framework: The compound contains a steroid-like structure, which is pivotal in many biological processes, notably in the development of hormones and vitamins.
  • Natural Occurrence: This compound can often be found in nature as a product of natural biosynthesis, highlighting the intricate chemistry that occurs within living organisms.
  • Biological Relevance: Compounds like this one may exhibit pharmacological activities and could be crucial in the development of drugs or therapies, especially in cancer research.
  • Synthesis Challenges: The synthesis of such complex molecules presents challenges in controlling stereochemistry and achieving high yields, making it a prominent subject of study in synthetic organic chemistry.
  • Environmental Importance: As part of synthetic studies, understanding this compound's reactivity can lead to advances in materials science and environmental chemistry, particularly in designing biodegradable materials.

As researchers continue to explore the potential of (17S)-10,13,17-trimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-diol, its unique properties are likely to provide new insights into both nature's design and innovative applications in various fields. Indeed, as we dive deeper into the world of chemical compounds, each molecule presents a unique story waiting to be told.

Synonyms
SCHEMBL11966148
AKOS001580989
AKOS021667384