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Estradiol

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Identification
Molecular formula
C18H24O2
CAS number
50-28-2
IUPAC name
(17S)-10,13,17-trimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-diol
State
State

Estradiol is typically in a solid state at room temperature.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
446.42
Boiling point (Kelvin)
719.57
General information
Molecular weight
272.38g/mol
Molar mass
272.3810g/mol
Density
1.1711g/cm3
Appearence

Estradiol is typically a white to creamy white crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of (17S)-10,13,17-trimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-diol

The solubility of (17S)-10,13,17-trimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-diol can be influenced by various factors.

This compound is a complex structure, and its solubility can be described as follows:

  • Polarity: Given its diol functional group, it exhibits some polar characteristics, which may enhance its solubility in polar solvents like water.
  • Hydrophobic Regions: Its large hydrophobic portions may limit solubility in highly polar environments, leading to better solubility in less polar organic solvents such as ethanol or acetone.
  • Concentration: Solubility may vary significantly with concentration; at lower concentrations, it might dissolve better in specific solvents.
  • Temperature Dependency: As with many organic compounds, solubility tends to increase with temperature, making heating a practical method to enhance dissolving capabilities.
  • Induced Solubility: Adding surfactants or co-solvents can also improve solubility in aqueous environments by minimizing hydrophobic interactions.

In summary, while (17S)-10,13,17-trimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-diol is anticipated to exhibit some degree of solubility, further experimental validation in various solvent systems is essential to fully understand its behavior in solution.

Interesting facts

Interesting Facts About (17S)-10,13,17-trimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-diol

This compound, though it may sound complex, falls into the fascinating world of organic chemistry, specifically as a steroid derivative. Its intricate structure showcases the beauty of carbon chemistry, featuring numerous interconnected rings that contribute to its unique properties.

Chemical Significance

Here are some compelling aspects of this compound:

  • Structural Complexity: The multi-ring structure is not just for show; it helps define the compound's reactivity and interactions with biological systems.
  • Biochemical Relevance: As a derivative of larger sterol compounds, it may play roles in hormonal functions and cellular signaling mechanisms within organisms.
  • Chirality: The 'S' notation in its name indicates the specific stereochemistry, influencing how the molecule interacts with enzymes and receptors.

Applications and Research

Researchers are particularly interested in compounds like this one for developing:

  • New pharmaceutical agents that target specific pathways in diseases.
  • Natural product synthesis mimicking biologically occurring steroids, which can lead to innovative drug designs.

Quote from Biology

As biologist Albert A. Michelson once said, "Science knows no country, because knowledge belongs to humanity, and is the torch which illuminates the world." Studying such compounds contributes to this collective knowledge and drives scientific advancement.

In summary, (17S)-10,13,17-trimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-diol serves as an intriguing example of how complex organic molecules are integral to both chemistry and biology. Continued exploration of its properties might reveal even more about its potential applications in health and medicine.

Synonyms
DTXSID00949723
17-methylandrosta-1,5-diene-3,17-diol