Ethinylestradiol | Solubility of Things

Identification

Molecular formula

C₂₀H₂₄O₂

CAS number

57-63-6

IUPAC name

(17S)-17-(2-chloroethynyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one

State

At room temperature, ethinylestradiol is in a solid state.

Melting point (Celsius)

182.00

Melting point (Kelvin)

455.15

Boiling point (Celsius)

370.50

Boiling point (Kelvin)

643.70

General information

Molecular weight

296.40g/mol

Molar mass

296.4030g/mol

Density

1.2300g/cm³

Appearence

Ethinylestradiol is usually present as a white to creamy-white crystalline powder. It is almost odorless.

Comment on solubility

Solubility Characteristics

The compound (17S)-17-(2-chloroethynyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopentaphenanthren-3-one exhibits distinct solubility behavior due to its complex structure. Understanding its solubility can be critical for applications in various fields, including pharmaceuticals and material science.

Key Aspects of Solubility

Polarity: The solubility of this compound may be influenced by the presence of functional groups such as chloro and hydroxy. Generally, compounds that are polar tend to dissolve well in polar solvents.
Solvent Compatibility: It is likely to be soluble in organic solvents like ethanol and acetone, while exhibiting limited solubility in water due to its hydrophobic components.
Temperature Effects: As with many organic compounds, an increase in temperature may enhance solubility, allowing for greater dissolution in a chosen solvent.

In summary, when considering (17S)-17-(2-chloroethynyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopentaphenanthren-3-one, its solubility profile is complex and multidimensional. Always remember that "the right solvent makes all the difference!"

Interesting facts

Interesting Facts about (17S)-17-(2-chloroethynyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one

This compound is a notable example of a complex steroid derivative, which has garnered attention in endocrine and medicinal chemistry. Here are some key points that highlight its significance:

Structural Complexity: The unique structure of this compound includes a cyclopenta[a]phenanthrene backbone, making it distinct from many conventional steroids. Its complex arrangement of rings allows for a variety of interactions with biological targets.
Functional Groups: The presence of the chloroethynyl and hydroxy functional groups play a vital role in determining the compound's biological activity. These groups can enhance receptor binding affinities and influence metabolic pathways.
Biological Relevance: Due to modifications in specific positions of the steroid core, this compound may exhibit unique pharmacological properties. It is of particular interest for research into potential therapeutic applications, particularly in hormonal therapies.
Synthetic Pathway: The synthesis of such complex compounds often involves multi-step chemical reactions, incorporating various synthetic strategies that could include functional group manipulations, cyclization, and regioselective reactions. This aspect provides rich territory for chemistry students and researchers alike.
Research Potential: Studies on compounds like this one can contribute to the development of novel drugs in the fields of oncology and endocrinology, allowing researchers to explore new avenues for treatment protocols.

As quoted in the scientific community, “Understanding the intricate details of steroid chemistry opens pathways to revolutionary advancements in medical science.” This statement rings true for compounds such as this, which are at the forefront of pharmaceutical innovation.

In conclusion, the exploration of (17S)-17-(2-chloroethynyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one signifies a fascinating intersection of chemistry and biology, appealing to both seasoned scientists and curious students.

Synonyms

NS00122796