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Gestodene

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Identification
Molecular formula
C21H26O2
CAS number
60282-87-3
IUPAC name
(17S)-17-hydroxy-13-methyl-17-propyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
State
State

At room temperature, gestodene is in a solid state.

Melting point (Celsius)
197.00
Melting point (Kelvin)
470.15
Boiling point (Celsius)
490.00
Boiling point (Kelvin)
763.15
General information
Molecular weight
310.45g/mol
Molar mass
310.4460g/mol
Density
1.0667g/cm3
Appearence

Gestodene appears as a white to off-white crystalline powder. It does not have any characteristic odor and it is soluble in common organic solvents.

Comment on solubility

Solubility of (17S)-17-hydroxy-13-methyl-17-propyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

The solubility of the compound (17S)-17-hydroxy-13-methyl-17-propyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one can be influenced by various factors, including its molecular structure and polarity.

In general, the solubility characteristics can be summarized as follows:

  • Polarity: This compound is likely to exhibit low to moderate polarity due to its large hydrophobic hydrocarbon skeleton. Compounds with similar structures often show limited solubility in polar solvents.
  • Solvent Compatibility: It may be better soluble in non-polar or slightly polar organic solvents, such as:
    • Hexane
    • Chloroform
    • Ether
  • Temperature Effects: As with many organic compounds, solubility typically increases with temperature, making hot solvents potentially more effective for dissolving this compound.
  • Hydrophobic Interactions: The presence of bulky hydrocarbon groups can lead to significant hydrophobic interactions, which might further limit solubility in water.

In conclusion, while specific solubility data may be limited, it is reasonable to predict that (17S)-17-hydroxy-13-methyl-17-propyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one will display low solubility in aqueous environments, favoring solubilization in organic solvents. As always, conducting empirical solubility tests will yield the most reliable information.

Interesting facts

Interesting Facts About (17S)-17-hydroxy-13-methyl-17-propyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

This compound, known for its complex structure and noteworthy properties, plays a significant role in various scientific fields, particularly in medicinal chemistry and biology. Here are some fascinating insights:

  • Stereochemistry: The compound features a specific stereochemistry denoted by the (17S) configuration. This designation suggests a unique spatial arrangement of its atoms, which can dramatically affect its biological activity and interaction with other molecules.
  • Biological Importance: Compounds similar to this one are often investigated for their potential therapeutic effects, particularly in hormone regulation and steroid hormone synthesis. Understanding their mechanisms can celebrate significant breakthroughs in treating hormone-related disorders.
  • Natural Occurrence: Structures akin to this compound are commonly found in nature, particularly in plants and animals as they often mimic steroid frameworks. This resemblance allows them to interact with biological receptors, leading to various physiological responses.
  • Research Applications: Scientists frequently study this compound and its analogs in drug development processes for their potential to act as steroidal drugs. Such research could lead to innovative treatments for a wide range of medical conditions.
  • Synthesis Challenges: The synthesis of this compound can be challenging due to its multi-ring structure and the necessity for precise stereocontrol. Chemists have developed various synthetic routes including complex reactions that require innovative strategies to ensure yield and purity.

“The study of such compounds not only enhances our understanding of chemistry but also opens avenues for life-saving medical applications.” This sentiment highlights why scientists are continually driven to learn more about complex molecules like this one, as they hold the keys to unlocking numerous challenges in health and medicine.