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Clostebol

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Identification
Molecular formula
C19H27ClO2
CAS number
1093-58-9
IUPAC name
(17S)-4-chloro-17-hydroxy-13,17-dimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
State
State

Clostebol is in a solid state at room temperature.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
510.20
Boiling point (Kelvin)
783.35
General information
Molecular weight
328.89g/mol
Molar mass
328.8850g/mol
Density
1.1706g/cm3
Appearence

Clostebol is a white crystalline powder at room temperature.

Comment on solubility

Solubility of (17S)-4-chloro-17-hydroxy-13,17-dimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

The solubility of the compound (17S)-4-chloro-17-hydroxy-13,17-dimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one displays several interesting characteristics:

  • Polar vs Nonpolar: Compounds with significant hydrophobic regions, like this one, often have limited solubility in water due to their nonpolar characteristics. This compound, with its complex cyclic structure and numerous hydrocarbon chains, is expected to exhibit low solubility in aqueous solutions.
  • Solvent Dependency: While water may not be an effective solvent for this substance, it may dissolve well in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO). This is due to the compatibility of organic solvents with similar nonpolar functional groups.
  • Temperature Influence: Temperature can greatly affect solubility. Typically, increasing the temperature enhances the solubility of solid compounds in liquid solvents, which could be a consideration when experimenting with this compound.

It is important to note that solubility can impact the bioavailability and efficacy of compounds in various applications. Therefore, understanding the solubility profile is crucial for researchers and chemists working with (17S)-4-chloro-17-hydroxy-13,17-dimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one.

Interesting facts

Interesting Facts about (17S)-4-chloro-17-hydroxy-13,17-dimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

This compound, commonly known as a derivative in the family of steroids, is characterized by its complex structure, which includes multiple rings fused together, typical of steroidal compounds. The specific stereochemistry indicated by the designation (17S) signifies the orientation of atoms around a particular carbon atom in this large molecule, affecting how it interacts with biological systems.

Key Features:

  • Biological Activity: Many steroid derivatives are crucial in the biological realm, often acting as hormones or signaling molecules.
  • Synthetic Utility: This compound can serve as an important intermediate in the synthesis of various pharmaceuticals, highlighting its relevance in medicinal chemistry.
  • Structure-Activity Relationship (SAR): The presence of chlorine and hydroxy groups can significantly alter the biological activity and the pharmacokinetic properties of steroidal compounds.

Furthermore, the unique hydrocarbon framework of this compound offers exciting avenues for research in organic synthesis. It demonstrates the intricate relationship between molecular structure and functionality, which is a critical concept in the field of chemistry.

Quote for Inspiration:

As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas." Thus, exploring compounds like this one can lead to unexpected breakthroughs in chemistry.

The study of such complex molecules encourages budding chemists and seasoned scientists alike to delve deeper into the world of organic chemistry and its applications in medicine and other fields.