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18-Fluorooctadecan-1-ol

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Identification
Molecular formula
C18H37FO
CAS number
407-57-2
IUPAC name
18-fluorooctadecan-1-ol
State
State
At room temperature, 18-Fluorooctadecan-1-ol is in a solid state. Its waxy texture and high melting point distinguish it from liquid alcohols of shorter chain lengths.
Melting point (Celsius)
42.00
Melting point (Kelvin)
315.15
Boiling point (Celsius)
428.50
Boiling point (Kelvin)
701.70
General information
Molecular weight
288.46g/mol
Molar mass
288.4620g/mol
Density
0.8833g/cm3
Appearence

18-Fluorooctadecan-1-ol appears as a white, waxy solid substance. It is typically odorless and has a greasy texture, characteristic of long-chain fatty alcohols.

Comment on solubility

Solubility of 18-Fluorooctadecan-1-ol

18-Fluorooctadecan-1-ol, with its unique structure, exhibits interesting solubility properties that can be influenced by several key factors:

  • Polarity: The presence of the hydroxyl (-OH) functional group tends to increase the solubility of the compound in polar solvents, like water. However, the long hydrophobic alkyl chain may hinder this solubility to some extent.
  • Hydrophobic Effect: The fluorine atom, which adds electronegative characteristics, may create some polar attraction, but the long carbon chain is predominantly nonpolar. This balance can make 18-fluorooctadecan-1-ol more soluble in nonpolar solvents, such as hexane or toluene.
  • Temperature: Temperature can play a significant role in solubility. Higher temperatures generally increase solubility in both polar and nonpolar solvents, allowing for better integration with solvent molecules.
  • Specific Interactions: Solvent-solute interactions, like hydrogen bonding, could enhance solubility in specific solvents. For instance, in alcohols or amines, this compound may demonstrate a greater affinity due to similar functional groups.

In summary, while 18-fluorooctadecan-1-ol can have some solubility in polar solvents due to its hydroxyl group, its long hydrophobic tail and the influence of the fluorine atom lead to more significant solubility in nonpolar organic solvents. Understanding these nuances is key to predicting the behavior of this compound in various chemical environments.

Interesting facts

Interesting Facts about 18-Fluorooctadecan-1-ol

18-Fluorooctadecan-1-ol is a fascinating compound that belongs to the class of fluorinated alcohols. Here are some intriguing points to consider:

  • Structure and Composition: As an alcohol, it contains a long hydrophobic hydrocarbon chain, which is punctuated by the presence of a fluorine atom. This unique fluorination can significantly alter the compound’s physical and chemical properties.
  • Applications: The compound is primarily utilized in synthetic chemistry and has potential applications in the development of surfactants, pharmaceuticals, and specialty chemicals. The incorporation of fluorine can enhance biodegradability and stability.
  • Biological Impact: Fluorinated compounds are known to exhibit varied biological activities. Studying 18-fluorooctadecan-1-ol provides insight into how fluorination affects the biological pathways, making it a subject of interest in biological and medicinal chemistry.
  • Environmental Considerations: Fluorinated compounds have gained attention for their impact on the environment. While they can improve certain properties, researchers must balance these benefits with potential ecotoxicity concerns.
  • Research Frontiers: Ongoing research into fluorinated alcohols like 18-fluorooctadecan-1-ol is crucial, as scientists explore new synthetic routes, reactivity patterns, and applications that could revolutionize various industrial sectors.

In the words of a famous chemist, "Creativity is the key to problem-solving; understanding the unique properties of compounds like 18-fluorooctadecan-1-ol paves the way for innovative solutions in chemistry."
This compound exemplifies the complexities and opportunities within chemical science, making it a compelling subject for further exploration and study.

Synonyms
18-Fluorooctadecanol
OCTADECANOL, 18-FLUORO-
omega-Fluorooctadecanol
BRN 1763601
408-44-6
DTXSID30193792
4-01-00-01893 (Beilstein Handbook Reference)
SCHEMBL8500529
DTXCID70116283