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tropinone

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Identification
Molecular formula
C8H13NO2
CAS number
532-24-1
IUPAC name
1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-2,4-dione
State
State

At room temperature, tropinone is a solid.

Melting point (Celsius)
40.00
Melting point (Kelvin)
313.15
Boiling point (Celsius)
216.00
Boiling point (Kelvin)
489.15
General information
Molecular weight
139.19g/mol
Molar mass
139.1880g/mol
Density
1.1545g/cm3
Appearence

Tropinone typically appears as a white crystalline solid.

Comment on solubility

Solubility of 1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-2,4-dione

The solubility of 1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-2,4-dione can be influenced by several factors, including its molecular structure and the presence of functional groups. This compound is characterized by a bicyclic structure with multiple substituents, which can impact its interaction with solvents.

Key Points on Solubility:

  • Polar vs. Nonpolar Solvents: The solubility in water, a polar solvent, may be limited due to the hydrophobic nature of the bicyclic framework, whereas nonpolar solvents could facilitate better solvation.
  • Temperature Effect: Generally, increasing temperature can enhance solubility due to increased molecular motion, leading to greater interaction with solvent molecules.
  • Concentration of Solution: High concentration of the compound may result in precipitation if the solution exceeds its solubility limit.
  • pH Dependence: The solubility of certain functional groups can be affected by the pH of the solution; thus, altering the pH may increase or decrease solubility.

As explored in various studies, understanding the solubility parameters can be crucial for applications such as drug formulation or chemical synthesis. One of the findings suggests that “a careful analysis of solvent interactions is necessary to predict solubility accurately.” Thus, while 1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-2,4-dione demonstrates unique solubility characteristics, further empirical data would better inform its practical applications.

Interesting facts

Interesting Facts about 1,8,8-Trimethyl-3-azabicyclo[3.2.1]octane-2,4-dione

1,8,8-Trimethyl-3-azabicyclo[3.2.1]octane-2,4-dione, often referred to in the context of its unique structural features, is a fascinating compound with various implications in chemistry and pharmacology. Here are some intriguing insights:

  • Structural Complexity: This compound is an example of a bicyclic structure, which is characterized by its two interconnected rings. The presence of the azabicyclo framework (containing nitrogen) adds to its reactivity and potential as a biological target.
  • Application Potential: Compounds like this one have shown promise in medicinal chemistry, particularly in developing new pharmaceutical agents due to their ability to mimic certain biological motifs.
  • Synthetic Interest: The synthetic routes to this compound can be quite challenging, often requiring innovative methods such as transition metal-catalyzed reactions or multistep organic processes.
  • Biological Role: Research suggests that derivatives of these types of compounds may exhibit interesting biological activities, including actions similar to those of neurotransmitters, which can be a focal point for neurological research.
  • Colorimetric Studies: This compound's diketone functional groups can engage in colorimetric reactions, making it useful for analytical chemistry applications in identifying or quantifying other compounds.

As chemists continue to explore its properties and potential applications, compounds like 1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-2,4-dione not only enhance our understanding of organic synthesis but also pave the way for innovations in drug design and development. It's a remarkable instance of how complex structures can lead to diverse functionalities in chemical research.

Synonyms
1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-2,4-dione
1,8,8-Trimethyl-3-azabicyclo(3.2.1)octane-2,4-dione
CAMPHORIMIDE(1,8,8-TRIMETHYL-3-AZABICYCLO(3.2.1)OCTANE-2,4-DIONE)
667-998-3
CAMPHORIMIDE
1972-03-8
1,8,8-Trimethyl-3-aza-bicyclo[3.2.1]octane-2,4-dione
(1S,5S)-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-2,4-dione
SCHEMBL2039071
3-Azabicyclo(3.2.1)octane-2,4-dione, 1,8,8-trimethyl-
DTXSID70941476
NRQVXWNPFZZDMQ-UHFFFAOYSA-N
CCG-49522
STK946037
AKOS001050312
AKOS016067614
AKOS022060581
CS-0279361
SR-01000638971-1
Z56876377
4-Hydroxy-1,8,8-trimethyl-3-azabicyclo[3.2.1]oct-3-en-2-one