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Epirubicin

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Identification
Molecular formula
C27H29NO11
CAS number
56420-45-2
IUPAC name
19-ethyl-19-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
State
State

At room temperature, Epirubicin is often found in a solid state, typically as a powder. When dissolved for medical applications, it is prepared as a liquid solution.

Melting point (Celsius)
224.00
Melting point (Kelvin)
497.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
543.52g/mol
Molar mass
543.5200g/mol
Density
1.3000g/cm3
Appearence

Epirubicin is typically available as a red-orange crystalline powder. It may also be provided in a solution form for medical and laboratory use, where it maintains a striking red color due to its chromophoric structure.

Comment on solubility

Solubility of 19-ethyl-19-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione (C27H29NO11)

The solubility of the compound 19-ethyl-19-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione is influenced by several factors, primarily due to its complex structure and functional groups. Here are some key points regarding its solubility:

  • Hydrophilicity: The presence of multiple hydroxy (-OH) groups, particularly the trihydroxy moiety, suggests that the compound is likely to be soluble in polar solvents.
  • Hydrophobic Regions: Despite its hydrophilic functionalities, the extensive polycyclic structure may result in some regions that are more hydrophobic, potentially affecting overall solubility in non-polar solvents.
  • Common Solvents: The compound may demonstrate varying solubility in solvents like water, alcohols, or dimethyl sulfoxide (DMSO).
  • Temperature Dependence: Solubility can also vary significantly with temperature; generally, increased temperature may enhance solubility for many compounds.
  • Concentration Effects: A saturated solution might lead to unique interactions or precipitation if excess solid is present.

In summary, while this compound likely exhibits solubility characteristics that favor polar solvents due to its functional groups, its overall solubility might be hindered by its complex structural nature. Further empirical testing is essential to determine the specific solubility profile in various solvents.

Interesting facts

Interesting Facts about 19-ethyl-19-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

This compound, known for its complex structure, belongs to a class of compounds with notable pharmacological and biological activities. Here are some fascinating insights into its characteristics:

  • Chemical Diversity: The presence of multiple functional groups, including hydroxyl (-OH) groups and a diaza structure, contributes to its reactivity and interaction with biological molecules.
  • Structural Complexity: With multiple rings in its framework, this compound showcases a pentacyclic structure which is a hallmark of many natural products, particularly those derived from plant sources.
  • Potential Therapeutic Applications: Compounds with similar structural motifs have been investigated for their potential use as anti-cancer agents, anti-inflammatory drugs, and in the treatment of various diseases due to their ability to modulate biological pathways.
  • Natural Occurrence: Understanding its biosynthesis could lead scientists to discover new natural products that provide insight into evolutionary adaptations in plants.
  • Research Interest: Ongoing studies are focused on elucidating the mechanism of action and bioavailability of this compound, which can provide valuable information for the development of new therapeutics.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” This compound encapsulates that philosophy by providing numerous avenues for exploration in both synthetic and natural chemistry.


Overall, as a scientist or a chemistry student, delving into such complex molecules not only enhances our understanding of chemical interactions but also opens doors to innovative solutions in health and medicine.