Skip to main content

Isatoic anhydride

ADVERTISEMENT
Identification
Molecular formula
C8H5NO3
CAS number
118-48-9
IUPAC name
1H-3,1-benzoxazine-2,4-dione
State
State

At room temperature, Isatoic anhydride is a solid. It exists in stable crystalline form and is handled as a solid material.

Melting point (Celsius)
238.00
Melting point (Kelvin)
511.15
Boiling point (Celsius)
220.00
Boiling point (Kelvin)
493.15
General information
Molecular weight
163.14g/mol
Molar mass
163.1410g/mol
Density
1.4280g/cm3
Appearence

Isatoic anhydride typically appears as a white or off-white crystalline solid. It is often found in the form of flakes or powder.

Comment on solubility

Solubility of 1H-3,1-benzoxazine-2,4-dione

1H-3,1-benzoxazine-2,4-dione, also known as a member of the benzoxazine family, exhibits unique solubility characteristics that are influenced by its molecular structure. When considering its solubility, several factors come into play:

  • Polarity: The presence of polar functional groups in the benzoxazine moiety contributes to its solubility in polar solvents.
  • Solvent Compatibility: This compound is generally soluble in a variety of solvents, particularly:
    • Water
    • Ethanol
    • Dimethyl sulfoxide (DMSO)
  • Temperature Effects: Solubility may increase with temperature, making it important to consider this variable in practical applications.

As with many organic compounds, one can expect varying solubility based on pH and the presence of other solutes. It is crucial to note that non-polar solvents generally yield lower solubility levels due to the compound's polar nature.

In conclusion, the solubility of 1H-3,1-benzoxazine-2,4-dione enhances its utility in diverse applications, emphasizing the importance of solvent choice in maximizing its potential.

Interesting facts

Exploring 1H-3,1-benzoxazine-2,4-dione

1H-3,1-benzoxazine-2,4-dione, often referred to as benzoxazine, is a fascinating compound with a rich chemistry that plays an essential role in various applications. Here are some intriguing aspects of this compound:

  • Structural Uniqueness: This compound features a distinctive bicyclic structure that combines a benzene ring with a nitrogen-containing heterocycle. This unique arrangement contributes to its chemical reactivity and potential usefulness in diverse chemistry fields.
  • Chemical Versatility: Benzoxazine derivatives are known for their ability to undergo various reactions, including polymerization, which makes them valuable in the development of advanced materials. They can be used to create adhesives, coatings, and even high-performance composites.
  • Potential Biological Activity: Research has suggested that certain derivatives of benzoxazines exhibit promising biological activity, including antimicrobial and anti-inflammatory properties. This raises the intriguing possibility of their use in medicinal chemistry.
  • Applications in Polymer Science: The polymerization of benzoxazine can lead to thermosetting networks, which are crucial for materials that require high thermal stability and mechanical strength, making them suitable for engineering applications.
  • Environmental Considerations: Due to a growing interest in environmentally friendly materials, the synthesis of benzoxazines is being explored with a focus on reducing toxic byproducts, aligning with the principles of green chemistry.

With its distinctive structure and versatile reactivity, 1H-3,1-benzoxazine-2,4-dione holds significant promise across various scientific disciplines, from materials science to medicinal chemistry. As research continues, the full potential of this compound and its derivatives will likely unfold, leading to innovative applications and solutions in chemistry.

Synonyms
Isatoic anhydride
118-48-9
1H-Benzo[d][1,3]oxazine-2,4-dione
2H-3,1-Benzoxazine-2,4(1H)-dione
ISATOIC ACID ANHYDRIDE
4H-3,1-Benzoxazine-2,4(1H)-dione
1H-3,1-benzoxazine-2,4-dione
N-Carboxyanthranilic anhydride
Isato acid anhydride
3,1-Benzoxazine-2,4(1H)-dione
Anthranilic acid, N-carboxy-, cyclic anhydride
HSDB 5017
Benzoic acid, 2-(carboxyamino)-, cyclic anhydride
EINECS 204-255-0
R8TFA74Y4U
NSC 104662
BRN 0136786
DTXSID6026955
1,2-dihydro-3,1-benzoxazine-2,4-dione
AI3-24983
2,4-dihydro-1H-3,1-benzoxazine-2,4-dione
NSC-29555
1h-benz(d)(1,3)oxazine-2,4-dione
NSC-104662
ISATOIC ACID,ANHYDRIDE
CHEMBL346059
DTXCID906955
2,4-dioxo-1,2-dihydro-4h-3,1-benzoxazine
EC 204-255-0
4-27-00-03330 (Beilstein Handbook Reference)
ISATOIC ACID ANHYDRIDE [HSDB]
2H-3,4(1H)-dione
Anthranilic acid, cyclic anhydride
CAS-118-48-9
MFCD00006700
UNII-R8TFA74Y4U
Anthranilic acid N-carboxylic acid anhydride
Isatoic anhydride, 96%
NCarboxyanthranilic anhydride
NCIOpen2_002029
SCHEMBL16251
Isatoic anhydride treated BSA
2,4-dioxo-1H-3,1-benzoxazine
2H3,1Benzoxazine2,4(1H)dione
4H3,1Benzoxazine2,4(1H)dione
HMS1607F14
1H-[3,1]benzoxazine-2,4-dione
CS-M0780
NSC29555
Tox21_201325
Tox21_303058
3,1-Benzoxazin-2,4-(1H)-dione
BBL009904
BDBM50201570
NSC104662
STK711078
1h-benzo[d][1,3]oxazine-2,4dione
2H-3,1-benzoxazine-2,4(1H)dione
AKOS000120179
1H-benzo[d][1,3]oxazin-2,4-dione
AC-3291
DB11593
FI01742
FS-3311
s12335
2H-3,1-benzoxazine-2,4-(1H)-dione
NCGC00164009-01
NCGC00164009-02
NCGC00257195-01
NCGC00258877-01
BP-10896
HY-76222
DB-041408
2H-benzo[d][1,3]oxazine-2,4(1H)-dione
Anthranilic acid, Ncarboxy, cyclic anhydride
I0081
NS00006862
1,2-Dihydro-4H-3,1-benzoxazine-2,4-dione
EN300-19149
I60039
Isatoic anhydride, technical, >=94% (HPLC)
Benzoic acid, 2(carboxyamino), cyclic anhydride
AE-641/30105041
Q11286492
F0036-0953
Z104472968