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Carbendazim

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Identification
Molecular formula
C9H9N3O2
CAS number
10605-21-7
IUPAC name
1H-benzimidazol-2-ylcarbamic acid
State
State

At room temperature, carbendazim is typically found in a solid state, specifically as a crystalline powder. This makes it suitable for use in various industrial applications, particularly in agriculture as a fungicide when formulated accordingly.

Melting point (Celsius)
302.00
Melting point (Kelvin)
575.15
Boiling point (Celsius)
728.00
Boiling point (Kelvin)
1 001.15
General information
Molecular weight
192.19g/mol
Molar mass
192.1940g/mol
Density
1.5000g/cm3
Appearence

Carbendazim is typically a white or off-white crystalline powder. Its appearance is consistent with many other organic solid compounds, displaying a fine particulate nature that is often associated with powders. It is stable under ordinary conditions.

Comment on solubility

Solubility of 1H-benzimidazol-2-ylcarbamic acid

1H-benzimidazol-2-ylcarbamic acid, known for its unique structural properties, exhibits distinctive solubility characteristics that are worth noting:

  • Aqueous Solubility: This compound is moderately soluble in water, which can be attributed to the presence of both carbamic acid and benzimidazole functional groups.
  • Solvent Dependence: Solubility may vary significantly with different solvents. For instance, it shows greater solubility in polar organic solvents such as ethanol and dimethyl sulfoxide (DMSO).
  • Effect of pH: The solubility is also affected by pH levels. In acidic conditions, the protonation of the nitrogen atoms may enhance solubility, while basic conditions could lead to neutral forms which may precipitate out.

In many cases, the solubility properties can be summarized with the phrase: "Like dissolves like." Therefore, understanding the solubility of 1H-benzimidazol-2-ylcarbamic acid necessitates consideration of its molecular interactions within different environments. This compound serves as a prime example of how molecular structure intricately influences solubility profiles.

Interesting facts

Interesting Facts about 1H-benzimidazol-2-ylcarbamic acid

1H-benzimidazol-2-ylcarbamic acid is a fascinating compound that bridges the fields of medicinal chemistry and biochemistry. Here are some intriguing aspects of this compound:

  • Structural Significance: This compound features a benzimidazole core, a bicyclic structure that has shown substantial relevance in pharmacology due to its role in various bioactive molecules.
  • Biological Activity: Compounds like 1H-benzimidazol-2-ylcarbamic acid are often studied for their potential as antimicrobial and antitumor agents, contributing to the ongoing search for new pharmaceuticals.
  • Applications: The versatility of the benzimidazole moiety enables its use in diverse applications, including agriculture and environmental science, where it serves as a basis for various fungicides and pesticides.
  • Mechanistic Insights: Understanding the way this compound interacts with biological systems can reveal critical insights into developed resistance mechanisms in pathogens, paving the way for better therapeutic strategies.
  • Research Frontiers: Ongoing research explores the modification of its structure to enhance efficacy and reduce toxicity, demonstrating the dynamic nature of chemical innovation.

In summary, 1H-benzimidazol-2-ylcarbamic acid plays a pivotal role in many scientific fields, showcasing the profound impact that a single compound can have on medicine, agriculture, and beyond. As quoted by renowned chemist Marie Curie:

“Nothing in life is to be feared, it is only to be understood.”

Continued exploration and understanding of such compounds bring us a step closer to unlocking their full potential.

Synonyms
2-BENZIMIDAZOLECARBAMIC ACID
Benzimidazole carbamate
2-Benzimidazolylcarbamic acid
Carbamic acid, 1H-benzimidazol-2-yl-
BRN 0958262
4N6W49USD5
DTXSID30171772
BENZIMIDAZOLE-2-CARBAMATE, N-
N-1H-BENZIMIDAZOL-2-YLCARBAMIC ACID
CARBAMIC ACID, N-1H-BENZIMIDAZOL-2-YL-
DTXCID2094263
18538-45-9
1H-benzimidazol-2-ylcarbamic acid
Carbamic acid, 1H-benzimidazol-2-yl- (9CI)
N-(1H-1,3-benzodiazol-2-yl)carbamate
2-benzimidazolecarbamic
UNII-4N6W49USD5
SCHEMBL204726
benzimidazol-2-ylcarbamic acid
AKOS006279831
DB-275213
C22848