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Thiourea benzimidazole

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Identification
Molecular formula
C8H8N4O
CAS number
2050-84-2
IUPAC name
1H-benzimidazol-2-ylurea
State
State
At room temperature, this compound is in a solid state, characterized by its crystalline form.
Melting point (Celsius)
231.00
Melting point (Kelvin)
504.15
Boiling point (Celsius)
355.00
Boiling point (Kelvin)
628.15
General information
Molecular weight
176.20g/mol
Molar mass
176.2010g/mol
Density
1.4700g/cm3
Appearence

This compound appears as a white crystalline solid. It is common in laboratories and might have a varying texture or granularity depending on its processing.

Comment on solubility

Solubility of 1H-benzimidazol-2-ylurea

1H-benzimidazol-2-ylurea is a compound with notable solubility characteristics that depend on various factors such as temperature and the presence of other substances. Here are some insights into its solubility:

  • Solvent Properties: This compound is generally soluble in polar solvents like water and methanol.
  • Temperature Dependence: Its solubility tends to increase with higher temperatures, making it a versatile compound in various applications.
  • pH Influence: The solubility can also be affected by the pH of the solution. In more acidic or basic conditions, the ionization of the compound may promote greater solubility.
  • Comparison with Similar Compounds: When compared to other benzimidazole derivatives, 1H-benzimidazol-2-ylurea exhibits a moderate level of solubility which can be advantageous in certain chemical reactions and formulations.

In summary, understanding the solubility of 1H-benzimidazol-2-ylurea is crucial for its application in scientific research and industry. Factors such as solvent choice, temperature, and pH play significant roles in how well this compound can dissolve, impacting its usability and effectiveness.

Interesting facts

Interesting Facts about 1H-benzimidazol-2-ylurea

1H-benzimidazol-2-ylurea is a fascinating compound that combines elements of both benzimidazole and urea functionalities, showcasing a unique intersection of organic chemistry. This molecule is not just another compound; it has **significant biological implications** that make it a subject of interest in medicinal chemistry.

Key Highlights:

  • Pharmacological Potential: 1H-benzimidazol-2-ylurea derivatives have been explored for their potential as anti-cancer agents. They exhibit interactions that can inhibit various targets within cancer cells, making them a promising area for drug design.
  • Pest Management: The compound has also been investigated for its agricultural applications, particularly in the development of pesticides and herbicides that leverage its unique chemical structure.
  • Structural Properties: The combination of the benzimidazole ring—a bicyclic structure that is common in many pharmaceutical agents—with the urea moiety, allows for a diverse range of ^functionalization^ opportunities that can lead to variations in activity and selectivity.
  • Research Applications: This compound continues to be of interest in various scientific fields, including **biochemistry**, **organic synthesis**, and **material science**, as researchers explore its utility in different contexts.

One notable feature of 1H-benzimidazol-2-ylurea is that it serves as a versatile building block in synthetic chemistry. As noted by researchers, its ability to participate in various chemical reactions expands its adaptability in forming more complex derivatives.
For example, in a study, scientists remarked, "The incorporation of benzimidazole scaffolds in drug molecules can significantly enhance their bioactivity."

Moreover, the exploration of 1H-benzimidazol-2-ylurea underlines the critical relationship between molecular structure and biological activity, making it an invaluable subject of study for those pursuing innovation in the fields of pharmacology and agrochemistry.

Synonyms
2-Benzimidazolylurea
Benzimidazol-2-ylurea
24370-25-0
2-Benzimidazoleurea
2-Ureidobenzimidazole
Urea, 1H-benzimidazol-2-yl-
Urea, (2-benzimidazolyl)-
Y7B0YQ5TBD
DTXSID3024574
NSC-84166
N-1H-benzimidazol-2-ylurea
DTXCID104574
RefChem:465535
2-BZIU
246-209-2
1H-Benzimidazol-2-ylurea
2-Benzimidazolylurea, 98%
CCRIS 5968
EINECS 246-209-2
UNII-Y7B0YQ5TBD
NSC 84166
BRN 0164344
Urea, benzimidazol-2-yl-
SCHEMBL707208
SCHEMBL7788764
CHEMBL1576153
SCHEMBL29776932
LNYZEFQMIURYEI-UHFFFAOYSA-
N-(1H-Benzimidazol-2-yl)urea #
NSC84166
Tox21_200170
AKOS009156691
UREA, N-1H-BENZIMIDAZOL-2-YL-
NCGC00091822-01
NCGC00091822-02
NCGC00257724-01
CAS-24370-25-0
DB-046425
NS00027636
Q27294347
InChI=1/C8H8N4O/c9-7(13)12-8-10-5-3-1-2-4-6(5)11-8/h1-4H,(H4,9,10,11,12,13)