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Trimethoprim hydrochloride

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Identification
Molecular formula
C20H22ClN5O4
CAS number
61394-01-8
IUPAC name
1H-imidazol-3-ium-5-ylmethyl 3,4,5-trimethoxybenzoate;chloride
State
State

At room temperature, this compound is a solid.

Melting point (Celsius)
199.00
Melting point (Kelvin)
472.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
407.89g/mol
Molar mass
290.7400g/mol
Density
1.3300g/cm3
Appearence

It appears as a white crystalline powder. It is odorless and known for its solubility in water and alcohol.

Comment on solubility

Solubility of 1H-imidazol-3-ium-5-ylmethyl 3,4,5-trimethoxybenzoate;chloride

The solubility characteristics of 1H-imidazol-3-ium-5-ylmethyl 3,4,5-trimethoxybenzoate;chloride can be quite intriguing due to its unique structural composition. Here are some key points to consider:

  • Polar and Non-Polar Interactions: The presence of the 3,4,5-trimethoxy groups introduces both polar (methoxy groups) and non-polar characteristics, influencing solubility in various solvents.
  • Aqueous Solubility: Typically, imidazole derivatives tend to display good solubility in water due to their ionic nature; however, the extent may vary based on substituents.
  • Organic Solvents: This compound might exhibit a greater solubility in organic solvents like ethanol and dimethyl sulfoxide (DMSO), particularly because of its alkyl and aromatic components.
  • Temperature Influence: Increasing the temperature can generally enhance solubility for many compounds, so conducting experiments at elevated temperatures could yield insightful data.

In summary, the solubility of 1H-imidazol-3-ium-5-ylmethyl 3,4,5-trimethoxybenzoate;chloride is a multifaceted aspect that warrants thorough investigation to understand its behavior in various environments. As with many chemical compounds, solubility is not merely about the solvent type but also involves considering the overall interactions with the surrounding molecules.

Interesting facts

Interesting Facts About 1H-imidazol-3-ium-5-ylmethyl 3,4,5-trimethoxybenzoate; chloride

The compound 1H-imidazol-3-ium-5-ylmethyl 3,4,5-trimethoxybenzoate; chloride is a fascinating example of a complex organic compound that merges the functionalities of imidazolium ions and aromatic esters. Here are some intriguing aspects of this compound:

  • Unique Structure: The presence of an imidazolium cation imbues this compound with distinctive properties, including the ability to act as a strong nucleophile and engage in various chemical transformations.
  • Applications: Compounds like this are often studied for their potential applications in fields such as medicinal chemistry, organic synthesis, and materials science. For instance, they may exhibit antimicrobial or antifungal properties.
  • Functional Groups: The inclusion of trimethoxy functionalities is noteworthy as these groups significantly enhance the compound's solubility and biological activity, making it a subject of interest for drug design.
  • Chloride Salts: The chloride component serves not only to balance the charge but also influences the compound’s solubility and reactivity, essential for various synthetic pathways.

Moreover, researchers are continuously investigating the structure-activity relationships (SAR) of this compound. Understanding how structural components affect biological behaviors can lead to the development of new therapeutic agents. As noted by chemists, “The beauty of organic chemistry lies in its endless possibilities for innovation.”

Thus, 1H-imidazol-3-ium-5-ylmethyl 3,4,5-trimethoxybenzoate; chloride exemplifies not only the complexity of organic molecules but also their potential to inspire groundbreaking advancements in various scientific domains.

Synonyms
18429-74-8
BENZOIC ACID, 3,4,5-TRIMETHOXY-, IMIDAZOL-4-YLMETHYL ESTER, MONOHYDROCHLORIDE
3,4,5-Trimethoxybenzoic acid imidazol-4-ylmethyl ester hydrochloride
Imidazole-4-methanol, 3,4,5-trimethoxybenzoate (ester), hydrochloride