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2-Mercaptoimidazole

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Identification
Molecular formula
C3H4N2S
CAS number
872-80-6
IUPAC name
1H-imidazole-2-thiol
State
State

At room temperature, 2-Mercaptoimidazole is a solid.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.00
Boiling point (Celsius)
289.00
Boiling point (Kelvin)
562.00
General information
Molecular weight
100.14g/mol
Molar mass
100.1430g/mol
Density
1.3200g/cm3
Appearence

2-Mercaptoimidazole generally appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 1H-imidazole-2-thiol

1H-imidazole-2-thiol, a compound with the formula C3H4N2S, exhibits interesting solubility characteristics that are influenced by its chemical structure. This compound is generally considered to be:

  • Soluble in water: Due to the presence of the thiol (-SH) group, which is polar, 1H-imidazole-2-thiol exhibits a significant ability to dissolve in aqueous solutions.
  • Soluble in organic solvents: This compound can also be soluble in various organic solvents like ethanol and methanol, thanks to its aromatic imidazole ring that enhances its compatibility with non-polar environments.
  • Weakly soluble in non-polar solvents: Its solubility in non-polar solvents is limited, which is expected given its polar characteristics.

In conclusion, the solubility of 1H-imidazole-2-thiol demonstrates a balance between polar and non-polar characteristics, making it adaptable in various chemical environments. As one often states in chemistry, "The solubility of a compound is a crucial factor that dictates its reactivity and use in different applications."

Interesting facts

Interesting Facts about 1H-Imidazole-2-thiol

1H-Imidazole-2-thiol, also known as 2-thioimidazole, is a fascinating compound with a rich chemistry that impacts various fields. Here are some intriguing aspects:

  • Biological Significance: This compound is a key player in the biochemical landscape, particularly in the formation of certain metalloenzymes, where it can act as a ligand to transition metals.
  • Pharmaceutical Applications: 1H-Imidazole-2-thiol has been explored for its potential roles in drug design and development, particularly due to its ability to modulate biological activity.
  • Antioxidant Properties: Research indicates that compounds like 1H-imidazole-2-thiol can exhibit antioxidant activities, which can help in combating oxidative stress—a contributing factor in many diseases.
  • Coordination Chemistry: The presence of sulfur and nitrogen in 1H-imidazole-2-thiol allows it to form interesting coordination complexes with metal ions, leading to a variety of innovative applications in materials science and catalysis.

As a scientist or chemistry student, understanding the multifunctional properties of 1H-imidazole-2-thiol provides critical insights into:

  1. Its role in enzyme catalysis and structural biology.
  2. Its potential in developing treatments for diseases related to oxidative damage.
  3. Exploration in coordination compounds that can serve in advanced chemical reactions.

This compound stands as a testament to the intricate connections between structure and function in chemistry, making it an exciting topic for anyone interested in the molecular underpinnings of life and materials.