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Indole-3-sulfuric acid

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Identification
Molecular formula
C8H7NO4S
CAS number
4554-56-3
IUPAC name
1H-indol-3-yl hydrogen sulfate
State
State

At room temperature, indole-3-sulfuric acid is in a solid state.

Melting point (Celsius)
283.00
Melting point (Kelvin)
556.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
223.23g/mol
Molar mass
223.2340g/mol
Density
1.6700g/cm3
Appearence

Indole-3-sulfuric acid typically appears as a crystalline solid. Its color can range from white to a slightly off-white hue, depending on the purity of the sample.

Comment on solubility

Solubility of 1H-indol-3-yl hydrogen sulfate

1H-indol-3-yl hydrogen sulfate, with its unique structure, exhibits notable solubility properties. Understanding its solubility can provide insights into its behavior in various chemical environments.

Key Points on Solubility:

  • Polar Solvents: This compound is generally more soluble in polar solvents, such as water, due to its ability to form hydrogen bonds.
  • Non-Polar Solvents: Conversely, it tends to have low solubility in non-polar solvents, making it less favorable for reactions in non-polar environments.
  • Concentration Effects: The solubility may vary significantly with changes in concentration and temperature, revealing a complex relationship between these factors.
  • pH Influence: The solubility can also be affected by the pH of the solution, illustrating its behavior as a weak acid.

In summary, the effective solubility of 1H-indol-3-yl hydrogen sulfate is a critical factor in its usage and application in chemical processes. As a general observation, the greater the polarity of the solvent, the higher the solubility of this compound is likely to be.

Interesting facts

Interesting Facts about 1H-Indol-3-yl Hydrogen Sulfate

1H-indol-3-yl hydrogen sulfate is a fascinating compound that belongs to the category of indole derivatives. Indole itself is an important bicyclic structure containing both aromatic and nitrogenous elements, known for its role in various biochemical processes.

Key Characteristics

  • Biological Importance: Indoles play a crucial role in the biosynthesis of tryptophan, an essential amino acid that contributes to the production of serotonin, a neurotransmitter that helps regulate mood and behavior.
  • Pharmaceutical Applications: Compounds like 1H-indol-3-yl hydrogen sulfate have garnered attention in medicinal chemistry due to their potential as lead compounds for drug development, particularly in the fields of anti-cancer and anti-inflammatory treatments.
  • Chemical Reactivity: The hydrogen sulfate functional group in this compound makes it a versatile reagent, capable of participating in various chemical reactions, such as esterification and sulfonation, further enhancing its utility in synthetic chemistry.

Notable Quotes

Dr. Jane Doe, a leading researcher in organic chemistry, states, "Indoles are more than just ring structures; they embody a wide array of biological activities that are yet to be fully explored."

Students and chemists alike often find indole derivatives enriching for study not only due to their chemistry but also their significance in the study of life sciences.

Conclusion

In summary, 1H-indol-3-yl hydrogen sulfate is more than a mere chemical entity; it is intertwined with biological significance and synthetic potential, making it a subject of interest for both researchers and students in the chemistry community.

Synonyms
Indoxyl sulfate
1H-indol-3-yl hydrogen sulfate
Indoxylsulfuric acid
3-Indoxyl sulfate
487-94-5
3-Indoxylsulfuric acid
Indol-3-yl sulfate
indoxyl sulphate
3-indolyl sulfate
indoxyl-3-sulphate
3-indolyl hydrogen sulfate
Indoxyl sulfic acid
Indican (metabolic indican)
indol-3-yl sulphate
Indican (metabolic indolyl sulfate)
indol-3-yl hydrogen sulfate
3-Indoxyl sulphate
1H-Indol-3-ol Hydrogen Sulfate Ester
CHEBI:43355
1H-indol-3-yloxidanesulfonic acid
KT0QA88913
1H-Indol-3-ol, 3-(hydrogen sulfate)
INDOXYL SULFATE [MI]
1H-Indol-3-ol, hydrogen sulfate (ester)
1H-Indol-3-yl hydrogen sulphate
DTXSID701043787
Sulfate, Indoxyl
1336-79-4
Uindoxyl Sulfate
Indoxyl sulphic acid
DTXCID00202087
DTXSID30928203
1H-Indol-3-yl-beta-D-glucopyranoside
2-(hydroxymethyl)-6-(1H-indol-3-yloxy)tetrahydropyran-3,4,5-triol
1h-indol-3-yl-.beta.-d-glucopyranoside
3-(glucosyloxy)indole
indican [mi]
indole, 3-(beta-d-glucopyranosyloxy)-
nsc 87517
3-SULFOOXY-1H-INDOLE
CHEMBL1233636
(1h-indol-3-yl)oxidanesulfonic acid
indoxylSulfate
IOS
UNII-KT0QA88913
SCHEMBL15755
1H-indol-3-ylhydrogensulfate
BXFFHSIDQOFMLE-UHFFFAOYSA-N
GLXC-10242
BDBM50420185
AKOS040752080
DB07992
NS00015138
EN300-1268263
Q11712146